Results 111 to 120 of about 103,825 (319)
Nuclear Physics B - Proceedings Supplements, 1996 14 pages; latex; an error has been ...
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The existence and characterisation of duality of Markov processes in the Euclidean space [PDF]
This thesis examines the existence of dualMarkov processes and presents the full characterization of Markov processes in Euclidean space equipped with the natural order (the Pareto order).
Lee, Rui Xin
core
Poincaré duality in Hochschild (co)homology [PDF]
, 2006 These are notes on van den Bergh’s analogue of Poincar´e duality in Hochschild (co)homology [VdB98]. They are based on survey talks that I gave in 2006 in G¨ottingen, Cambridge and Warsaw and consist of an elementary explanation of the proof in terms ...
Kraehmer, U.
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Duality modules and Morita duality
Journal of Algebra, 1989 Let \({}_RU_S\) be endowed with a Hausdorff topology such that the elements of \(S\) induce continuous \(R\)-homomorphisms, \(R\text{-Top}\) be the category of Hausdorff topological left \(R\)-modules. \(U\)-duality between full subcategories \(\mathcal C\subseteq R\)-Top and \(\mathcal D\subseteq \text{Mod-}S\) is defined by functors \(\text{Cont}_R(-,
Zelmanowitz, J.M, Jansen, W
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Model Selection Criteria Using Divergences
Entropy, 2014 In this note we introduce some divergence-based model selection criteria. These criteria are defined by estimators of the expected overall discrepancy between the true unknown model and the candidate model, using dual representations of divergences and ...
Aida Toma
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Inf. Res., 2002 Knowledge Management (KM) is a field that has attracted much attention both in academic and practitioner circles. Most KM projects appear to be primarily concerned with knowledge that can be quantified and can be captured, codified and stored - an approach more deserving of the label Information Management. Recently there has been recognition that some
Hildreth, Paul, Kimble, Chris
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source