Results 131 to 140 of about 529,479 (293)
Jordan duality and Freudenthal duality
Journal of Physics: Conference Series, 2013 We define a Jordan duality A → A* on the quantised charges A of five dimensional black holes and strings and an analogous Freudenthal duality x → on the quantised charges x of four dimensional stringy black holes, both of which are distinct from U-duality but leave the lowest order entropy invariant.
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Hidden Symmetries of M-Theory and Its Dynamical Realization
Symmetry, Integrability and Geometry: Methods and Applications, 2008 We discuss hidden symmetries of M-theory, its feedback on the construction of the M-theory effective action, and a response of the effective action when locality is preserved.
Alexei J. Nurmagambetov
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Dualities in equivariant Kasparov theory
, 2009 We study several duality isomorphisms between equivariant bivariant K-theory groups, generalising Kasparov's first and second Poincare duality isomorphisms.
Emerson, Heath, Meyer, Ralf
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
The duality of the nature of dialogue in philosophy and medical practice
Studia Humanitatis, 2019 The article analyses the duality of nature in relationships between the doctor and the patient. This research was conducted in the context of M. Buber’s philosophy.
Koroleva Elena Pavlovna +1 more
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