Results 131 to 140 of about 2,001,040 (344)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Color-kinematics duality for QCD amplitudes [PDF]
, 2015 A bstractWe show that color-kinematics duality is present in tree-level amplitudes of quantum chromodynamics with massive flavored quarks. Starting with the color structure of QCD, we work out a new color decomposition for n-point tree amplitudes in a ...
H. Johansson, Alexander Ochirov
semanticscholar +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Punctured Haag duality in locally covariant quantum field theories
, 2004 We investigate a new property of nets of local algebras over 4-dimensional globally hyperbolic spacetimes, called punctured Haag duality. This property consists in the usual Haag duality for the restriction of the net to the causal complement of a point $
Brunetti +7 more
core +2 more sources
The composite particle duality: a new class of topological quantum matter
New Journal of PhysicsThe composite particle duality extends the notions of both flux attachment and statistical transmutation in spacetime dimensions beyond 2 + 1D. It constitutes an exact correspondence that can be understood either as a theoretical framework or as a ...
Gerard Valentí-Rojas +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Axioms, 2016 We study densely defined unbounded operators acting between different Hilbert spaces. For these, we introduce a notion of symmetric (closable) pairs of operators.
Palle Jorgensen, Feng Tian
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Duality Rotations in Nonlinear Electrodynamics and in Extended Supergravity
, 2008 We review the general theory of duality rotations which, in four dimensions, exchange electric with magnetic fields. Necessary and sufficient conditions in order for a theory to have duality symmetry are established.
Aschieri, Paolo +2 more
core +2 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source