Results 61 to 70 of about 900,248 (299)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

No U(1) ‘electric-magnetic’ duality in Einstein gravity

Journal of High Energy Physics
We revisit the question of whether classical general relativity obeys, beyond the linearised order, an analogue of the global U(1) electric-magnetic duality of Maxwell theory, with the Riemann tensor playing the role analogous to the field strength ...
Ricardo Monteiro
doaj   +1 more source

Discrete symmetries in Heterotic/F-theory duality and mirror symmetry

Journal of High Energy Physics, 2017
We study aspects of Heterotic/F-theory duality for compactifications with Abelian discrete gauge symmetries. We consider F-theory compactifications on genus-one fibered Calabi-Yau manifolds with n-sections, associated with the Tate-Shafarevich group ℤ n $
Mirjam Cvetič, Antonella Grassi, Maximilian Poretschkin   +2 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Seiberg-Witten map for D-branes in large R-R field background

Journal of High Energy Physics, 2021
We obtain a Seiberg-Witten map for the gauge sector of multiple Dp-branes in a large R-R (p − 1)-form field background up to the first-order in the inverse R-R field background.
Chen-Te Ma
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Particle-vortex duality of two-dimensional Dirac fermion from electric-magnetic duality of three-dimensional topological insulators [PDF]

, 2015
Particle-vortex duality is a powerful theoretical tool that has been used to study bosonic systems. Here we propose an analogous duality for Dirac fermions in 2+1 dimensions. The physics of a single Dirac cone is proposed to be described by a dual theory,
M. Metlitski, A. Vishwanath
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Non-linear duality invariant partially massless models?

Physics Letters B, 2016
We present manifestly duality invariant, non-linear, equations of motion for maximal depth, partially massless higher spins. These are based on a first order, Maxwell-like formulation of the known partially massless systems.
D. Cherney, S. Deser, A. Waldron, G. Zahariade   +3 more
doaj   +1 more source

Higher-derivative field redefinitions in the presence of boundary

European Physical Journal C: Particles and Fields, 2022
Recently it has been proposed that the consistency with T-duality requires the effective action of string theory at order $$\alpha '^n$$ α ′ n to satisfy the least action principle provided that the values of the massless fields and their derivatives up ...
Mohammad R. Garousi
doaj   +1 more source