Results 41 to 50 of about 10,808 (265)
String theory dualities from M-theory [PDF]
Nuclear Physics B, 1996 18 pages, uses harvmac ...
openaire +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Non-invertible T-duality at any radius via non-compact SymTFT
SciPost PhysicsWe extend the construction of the T-duality symmetry for the 2d compact boson to arbitrary values of the radius by including topological manipulations such as gauging continuous symmetries with flat connections.
Riccardo Argurio, Andrés Collinucci, Giovanni Galati, Ondrej Hulik, Elise Paznokas
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New T-duality for Chern-Simons theory
Journal of High Energy Physics, 2019 It has recently pointed out that a four-dimensional analog of Chern-Simons theory provides an elegant framework for understanding integrable models with spectral parameters.
Masahito Yamazaki
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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Level-rank duality in Chern–Simons theory from a non-supersymmetric brane configuration
Physics Letters B, 2014 We derive level-rank duality in pure Chern–Simons gauge theories from a non-supersymmetric Seiberg duality by using a non-supersymmetric brane configuration in type IIB string theory. The brane configuration consists of fivebranes, N D3 antibranes and an
Adi Armoni, Edwin Ireson
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Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Markuschevich bases and duality theory [PDF]
Transactions of the American Mathematical Society, 1970 Several duality theorems concerning Schauder bases in locally convex spaces have analogues in the theory of Markuschevich bases. For example, a locally convex space with a Markuschevich basis is semireflexive iff the basis is shrinking and boundedly complete.
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source