Results 171 to 180 of about 13,612 (242)
The deubiquitinating enzyme Cezanne stabilizes BRCA1 by counteracting APC/C and Ube2S-dependent Lys11-linked ubiquitination. [PDF]
Wang L, Wu X, Paul A, Yao J, Wang B.
europepmc +1 more source
Computers and chess masters: The role of AI in transforming elite human performance
Abstract Advances in Artificial Intelligence (AI) have made significant strides in recent years, often supplementing rather than replacing human performance. The extent of their assistance at the highest levels of human performance remains unclear. We analyse over 11.6 million decisions of elite chess players, a domain commonly used as a testbed for AI
Merim Bilalić, Mario Graf, Nemanja Vaci
wiley +1 more source
Epsin1 enforces a condensation-dependent checkpoint for ubiquitylated cargo during clathrin-mediated endocytosis. [PDF]
Sarkar S +8 more
europepmc +1 more source
Abstract Social norms are powerful predictors of pro‐environmental behaviour. At the same time, conspiracy beliefs are prevalent that can reduce individuals' efforts to act pro‐environmentally and might impede the influence of social norms. Across three cross‐sectional studies in three countries (Germany, UK, US; total N = 1037), we investigated the ...
Kevin Winter +2 more
wiley +1 more source
The Role of Ubiquitination and Deubiquitination in the Pathogenesis of Acute Kidney Injury: Progress in Research. [PDF]
Zhou Y, Tao S, Liu L, Zhang L.
europepmc +1 more source
Background and Purpose EZH2 (enhancer of zeste homologue 2) inhibitors are an emerging class of drugs that target epigenetic regulation. However, their efficacy in solid tumours has been limited, partly due to drug‐induced upregulation of fatty acid synthesis.
Rui Cheng +10 more
wiley +1 more source
GPR34 Stabilized by Deubiquitinase USP8 Suppresses Ferroptosis of ATC. [PDF]
Yan B +7 more
europepmc +1 more source
Noninvasive prenatal diagnosis for monogenic diseases (NIPD‐M) to detect inherited mutations is performed in parallel with fetal fraction signatures, to detect various anomalies that may compromise diagnosis. An extra regression analysis may be necessary to resolve mosaic situations. ABSTRACT Noninvasive prenatal diagnosis relies on the analysis of the
Jean‐Louis Blouin +2 more
wiley +1 more source

