Results 121 to 130 of about 42,113 (251)
Can You Make Me Laugh? Toddlers’ and Parents’ Shared Positive Expressions in Playful Interactions
Social Development, Volume 34, Issue 3, August 2025.ABSTRACT Laughter and smiling are frequently experienced in social settings, yet more research is required to delineate their development and dynamics. We investigated toddlers’ and parents’ shared positive expressions in playful interactions. We observed eighty 30‐month‐old toddler–parent dyads in two phases of 8 min in length. In each, one person was
Anja Gampe +2 more
wiley +1 more source
MYH6‐Cre Insertion Accelerates Cardiac Phenotype in Dystrophic D2‐mdx Mice
The FASEB Journal, Volume 39, Issue 14, 31 July 2025.D2.B10‐Dmdmdx/J dystrophic mice were crossed with Tg(myh6‐cre)1Jmk/J mice to create a cardiac‐specific Myh6‐cre (Cre+) promoter region on the D2‐mdx background. Cre+ dystrophic animals demonstrate worse right and left ventricular systolic function, which correlates with increased cardiac‐specific fibrosis and ultimately reduced survival.
India K. Hawkins +6 more
wiley +1 more source
The population genetics of Duchenne: natural and artificial selection in Duchenne muscular dystrophy. [PDF]
, 1986 James Edwards
openalex +1 more source
Myostatin Levels in SMA Following Disease‐Modifying Treatments: A Multi‐Center Study
Annals of Clinical and Translational Neurology, Volume 12, Issue 7, Page 1368-1377, July 2025.ABSTRACT Objective This study investigated myostatin levels in SMA patients receiving disease‐modifying therapies (DMTs) to understand their relationship with treatment duration and functional status. Methods Our study includes both cross‐sectional and longitudinal analyses of myostatin levels in treated SMA patients.
Fiorella Piemonte +23 more
wiley +1 more source
Exosome-Mediated Benefits of Cell Therapy in Mouse and Human Models of Duchenne Muscular Dystrophy
Stem Cell Reports, 2018 Summary: Genetic deficiency of dystrophin leads to disability and premature death in Duchenne muscular dystrophy (DMD), affecting the heart as well as skeletal muscle.
Mark A. Aminzadeh +15 more
doaj
Defective myoblasts identified in Duchenne muscular dystrophy. [PDF]
, 1983 Helen M. Blau +2 more
openalex +1 more source
Translating Muscle RNAseq Into the Clinic for the Diagnosis of Muscle Diseases
Annals of Clinical and Translational Neurology, Volume 12, Issue 7, Page 1465-1479, July 2025.ABSTRACT Objective Approximately half of patients with hereditary myopathies remain without a definitive genetic diagnosis after DNA next‐generation sequencing (NGS). Here, we implemented transcriptome analysis of muscle biopsies as a complementary diagnostic tool for patients with muscle disease but no definitive genetic diagnosis after exome ...
Alba Segarra‐Casas +24 more
wiley +1 more source
Malignant Hyperthermia in Duchenne Muscular Dystrophy [PDF]
, 1983 A. Keith W. Brownell +6 more
openalex +1 more source
Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction
Advanced Healthcare Materials, Volume 14, Issue 17, July 4, 2025.This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi +13 more
wiley +1 more source