Results 111 to 120 of about 71,938 (313)

Human Galectin-1 Improves Sarcolemma Stability and Muscle Vascularization in the mdx Mouse Model of Duchenne Muscular Dystrophy [PDF]

open access: gold, 2019
Ryan D. Wuebbles   +6 more
openalex   +1 more source

Combating muscle atrophy: emerging therapeutic targets that are fiber‐type‐specific

open access: yesThe FEBS Journal, EarlyView.
Inflammation, denervation or decreased insulin signaling activate proteolysis and cause muscle wasting. Pathological conditions like obesity and DMD can also exacerbate atrophy via PGD2–RhoA–ROCK2 signaling. In contrast, exercise, dietary interventions, and pharmacological agents can activate Ca2+/calcineurin–NFAT and AMPK–PGC‐1α–MEF pathways ...
Samrat Chakraborty   +2 more
wiley   +1 more source

Author response: Beneficial impacts of neuromuscular electrical stimulation on muscle structure and function in the zebrafish model of Duchenne muscular dystrophy

open access: gold, 2021
Elisabeth A. Kilroy   +14 more
openalex   +1 more source

Back to Basics: A Curriculum to Address the Pediatric Cardiac Anesthesia Workforce Crisis

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT The field of pediatric cardiac anesthesia faces a critical workforce shortage. Survival of children with congenital heart disease (CHD) has improved dramatically, increasing both lifetime procedural demand and case complexity. At the same time, the supply of fellowship‐trained pediatric cardiac anesthesiologists is shrinking due to an aging ...
Lindsey Loveland, Susan C. Nicolson
wiley   +1 more source

Volitional exercise elicits physiological and molecular improvements in the severe D2.mdx mouse model of Duchenne muscular dystrophy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study investigated the effects of volitional exercise on muscle health in the more severe D2.mdx model of Duchenne muscular dystrophy (DMD). We showed that 8–10 weeks of a relatively high volume of voluntary wheel running (VWR) in D2.mdx animals augmented select muscle mass and normalized ex vivo muscle force compared to ...
Stephanie R. Mattina   +7 more
wiley   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar   +15 more
wiley   +1 more source

ST-segment elevation acute coronary syndrome in a child with Duchenne muscular dystrophy: a case report

open access: yesРоссийский кардиологический журнал
Introduction. Duchenne muscular dystrophy is an X-linked muscle disorder caused by the dystrophin absence. This leads to the death of muscle cells and cardiomyocytes and their subsequent replacement with adipose and fibrous tissue.
Z. G. Tatarintseva   +2 more
doaj   +1 more source

Can You See Us Play? Observing Inclusive Outdoor Play Behaviour Among Children With and Without Disabilities: A Mixed Methods Study

open access: yesChild: Care, Health and Development, Volume 52, Issue 1, January 2026.
ABSTRACT Background Outdoor play is essential for children's development. However, children with disabilities face barriers in outdoor play. In the Netherlands, there are limited opportunities for children with and without disabilities to play together.
R. Q. Beekhuizen   +9 more
wiley   +1 more source

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