Results 11 to 20 of about 15,396 (178)

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Analgesic Effects of Repetitive Transcranial Magnetic Stimulation at Different Stimulus Parameters for Neuropathic Pain: A Randomized Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives The aim of the present study was to investigate the analgesic effects of repetitive transcranial magnetic stimulation over the primary motor cortex (M1‐rTMS) using different stimulation parameters to explore the optimal stimulus condition for treating neuropathic pain.
Nobuhiko Mori, Koichi Hosomi, Asaya Nishi, Satoru Oshino, Haruhiko Kishima, Youichi Saitoh   +5 more
wiley   +1 more source

Quantitative Determination of Duloxetine Hydrochloride in Pharmaceuticals and Urine Using Prepared Ion Selective Membrane Electrode

International Journal of Electrochemical Science, 2012
A duloxetine ion selective membrane electrode is prepared. The electrode incorporates PVC membrane with duloxetine-silicomolybdate (DLX-SMA) ion pair complex with dioctylphthalate (DOP) as a plasticizer.
Reda A. Ammar, Haleema Otaif, Abdulrhman Al-Warthan   +2 more
doaj   +3 more sources

Duloxetine inhibits effects of MDMA ("ecstasy") in vitro and in humans in a randomized placebo-controlled laboratory study. [PDF]

PLoS ONE, 2012
This study assessed the effects of the serotonin (5-HT) and norepinephrine (NE) transporter inhibitor duloxetine on the effects of 3,4-methylenedioxy-methamphetamine (MDMA, ecstasy) in vitro and in 16 healthy subjects.
Cédric M Hysek, Linda D Simmler, Valentina G Nicola, Nerina Vischer, Massimiliano Donzelli, Stephan Krähenbühl, Eric Grouzmann, Jörg Huwyler, Marius C Hoener, Matthias E Liechti   +9 more
doaj   +1 more source

Possible Role of Cyclic AMP Response Element Binding/Brain-Derived Neurotrophic Factor Signaling Pathway in Mediating the Pharmacological Effects of Duloxetine against Methamphetamine Use-Induced Cognitive Impairment and Withdrawal-Induced Anxiety and Depression in Rats

Advanced Biomedical Research, 2019
Background: Duloxetine is used for treating depression and anxiety. The current study evaluated the effects of duloxetine against methamphetamine withdrawal-induced anxiety, depression, and motor disturbances and methamphetamine use-induced cognitive ...
Sanaz Ramezany Yasuj, Mona Nourhashemi, Saghar Keshavarzi, Majid Motaghinejad, Manijeh Motevalian   +4 more
doaj   +1 more source

Duloxetine: A Review of its Safety and Efficacy in the Management of Fibromyalgia Syndrome

Journal of Central Nervous System Disease, 2010
Fibromyalgia (FM) is a chronic disorder characterized by widespread pain and other associated symptoms including fatigue, insomnia, cognitive/memory problems, and even psychological distress. Duloxetine is one of three FDA approved medications (the other
Howard S. Smith, Donna Bracken, Joshua M. Smith   +2 more
doaj   +1 more source

Effect of duloxetine on neuropathic pain in patients intolerant to continuous administration of pregabalin

Spine Surgery and Related Research, 2017
Purpose: We examined duloxetine's effectiveness in the treatment of neuropathic pain in patients who were intolerant to continuous pregabalin administration.
Yohei Shimada, Kazuhide Inage, Sumihisa Orita, Masao Koda, Kazuyo Yamauchi, Takeo Furuya, Junichi Nakamura, Miyako Suzuki, Kazuki Fujimoto, Yasuhiro Shiga, Koki Abe, Hirohito Kanamoto, Masahiro Inoue, Hideyuki Kinoshita, Masaki Norimoto, Tomotaka Umimura, Kazuhisa Takahashi, Seiji Ohtori   +17 more
doaj   +1 more source

The Microglial Activation Inhibitor Minocycline, Used Alone and in Combination with Duloxetine, Attenuates Pain Caused by Oxaliplatin in Mice

Molecules, 2021
The antitumor drug, oxaliplatin, induces neuropathic pain, which is resistant to available analgesics, and novel mechanism-based therapies are being evaluated for this debilitating condition.
Kinga Sałat, Anna Furgała-Wojas, Robert Sałat   +2 more
doaj   +1 more source

Pharmacokinetics of duloxetine self-administered in overdose with quetiapine and other antipsychotic drugs in a Japanese patient admitted to hospital

Journal of Pharmaceutical Health Care and Sciences, 2021
Background Combinations of antidepressant duloxetine (at doses of 40–60 mg/day) and other antipsychotics are frequently used in clinical treatment; however, several fatal and nonfatal cases of duloxetine overdose have been documented.
Koichiro Adachi, Satoru Beppu, Kei Nishiyama, Makiko Shimizu, Hiroshi Yamazaki   +4 more
doaj   +1 more source

Importance of anogenital distance parameters on duloxetine success in women with stress urinary incontinence

Ginekologia Polska
OBJECTIVES: To clarify the impact of anogenital distance (AGD) on duloxetine success in the management of women with stress urinary incontinence (SUI). MATERIAL AND METHODS: Patients who have been diagnosed with SUI, were evaluated for inclusion in the ...
Mazhar Ortac, M. Firat Ozervarli, Ufuk Caglar, Resat Aydin, Senol Tonyali, Omer Sarilar, Faruk Ozgor   +6 more
doaj   +1 more source