Results 1 to 10 of about 3,520 (167)

Duloxetine hydrochloride loaded film forming dermal gel enriched with methylcobalamin and geranium oil attenuates paclitaxel-induced peripheral neuropathy in rats [PDF]

IBRO Reports, 2020
Objective: In attempt to conquer the major concerns of oral duloxetine hydrochloride (like low bioavailability, intolerable side-effects and no regeneration of demyelinated nerve fibres) for the management of chemotherapy-induced peripheral neuropathy ...
Jitender Madan
exaly   +4 more sources

Formulation and optimization of duloxetine hydrochloride buccal films: in vitro and in vivo evaluation [PDF]

Drug Delivery, 2017
Duloxetine hydrochloride (DH) is a serotonin–norepinephrine reuptake inhibitor (SSNRI) indicated for the treatment of depression. Duloxetine suffers from reduced oral bioavailability (≈50%) due to hepatic metabolism.
Ahmed Hassen Elshafeey
exaly   +3 more sources

Preparation and evaluation of duloxetine hydrochloride enteric-coated pellets with different enteric polymers [PDF]

Asian Journal of Pharmaceutical Sciences, 2017
The main purpose of the present study was to prepare duloxetine hydrochloride (DXH) enteric-coated pellets using different enteric polymers. Three layers (drug-loaded layer, barrier layer, and enteric-coated layer) were applied to the inert core pellets,
Dong Zhang
exaly   +4 more sources

A randomized, double-blinded, placebo-controlled clinical trial of duloxetine hydrochloride enteric-coated tablets in the treatment of refractory chronic cough [PDF]

BMC Pulmonary Medicine, 2023
Introduction Refractory cough, a chronic cough with an unclear diagnosis or poor treatment response. The symptoms are often stubborn and persistent, causing serious complications and lowering the patient's quality of life. Cough hypersensitivity syndrome
Shengyuan Wang, Shaohui Li, Heng Wu, Tongyangzi Zhang, Yixiao Chen, Yiqing Zhu, Siwan Wen, Cuiqin Shi, Li Yu, Xianghuai Xu   +9 more
doaj   +2 more sources

Quantitative Determination of Duloxetine Hydrochloride in Pharmaceuticals and Urine Using Prepared Ion Selective Membrane Electrode

International Journal of Electrochemical Science, 2012
A duloxetine ion selective membrane electrode is prepared. The electrode incorporates PVC membrane with duloxetine-silicomolybdate (DLX-SMA) ion pair complex with dioctylphthalate (DOP) as a plasticizer.
Reda A. Ammar, Haleema Otaif, Abdulrhman Al-Warthan   +2 more
exaly   +7 more sources

Disposable screen-printed sensors for determination of duloxetine hydrochloride

Chemistry Central Journal, 2012
A screen-printed disposable electrode system for the determination of duloxetine hydrochloride (DL) was developed using screen-printing technology.
Alarfaj Nawal A, Ammar Reda A, El-Tohamy Maha F   +2 more
doaj   +2 more sources

A green TLC–densitometric bioanalytical method for concurrent determination of duloxetine and risperidone in human plasma with in-silico DDI evaluation [PDF]

BMC Chemistry
Schizophrenia is a chronic, complex and severs psychiatric disorder that impacts men and women globally. The combined use of atypical antipsychotics; risperidone (RSP), and antidepressants medications; duloxetine hydrochloride (DLX), has grown more ...
Fatma Magdy, Raghda A. Emam, Basma H. Anwar   +2 more
doaj   +2 more sources

Simultaneous measurement of duloxetine hydrochloride and avanafil at dual-wavelength using novel ecologically friendly TLC-densitometric method: application to synthetic mixture and spiked human plasma with evaluation of greenness and blueness [PDF]

BMC Chemistry
The simultaneous assay of duloxetine hydrochloride (DLX) and avanafil (AVN) in their pure forms, synthetic mixtures, and spiked human plasma was achieved using a novel, eco-friendly, sensitive, and specific HPTLC methodology that have been established ...
Sayed M. Derayea, Hadeer A. Elhamdy, Mohamed Oraby, Khalid M. Badr El-Din   +3 more
doaj   +2 more sources

Efficacy of Duloxetine for Postspine Surgery Pain: A Systematic Review and Meta‐Analysis [PDF]

Brain and Behavior
Background Duloxetine, a serotonin and norepinephrine reuptake inhibitor (SNRI), is used to treat various health conditions, including major depressive disorder, generalized anxiety disorder, fibromyalgia, and off‐label for chemotherapy‐induced pain.
Abdulsalam Mohammed Aleid, Faisal Alshehri, Naif Alasiri, Fatimah Alhomoud, Shouq Alsaegh, Mohammed Alrasheed, Salem Aljaddua, Ali Alasiri, Asma Boukhari, Abdulmonem Ali Alhussain, Bipin Chaurasia, Saud Nayef Aldanyowi   +11 more
doaj   +2 more sources

Genome-wide association study −Driven drug repositioning for the treatment of insomnia [PDF]

Journal of Genetic Engineering and Biotechnology
Insomnia is a prevalent sleep disorder characterized by difficulty initiating or maintaining sleep, leading to severe health complications, increased mortality, and substantial socioeconomic burdens.
Rahmat Dani Satria, Wirawan Adikusuma, Usi Sukorini, Devy Eka Avitasari, Indra Sari Kusuma Harahap, Mohammad Hendra Setia Lesmana, Lalu Muhammad Irham, Nur Imma Fatimah Harahap, Pranindya Rinastiti, Donytra Arby Wardhana, Richardus Wisnandito Prabasaktya, Chiou-Feng Lin, Aprilia Paramitasari, Andrian Fajar Kusumadewi   +13 more
doaj   +2 more sources