Formulation study of duloxetine hydrochloride enteric-coated tablets
During storage, duloxetine hydrochloride may have an unexpected cross reaction with enteric coated acrylic resin, which may affect the product quality.
Jiang Guowei +4 more
doaj +2 more sources
Duloxetine Hydrochloride-Induced Oral Lichenoid Reaction: A Case Report [PDF]
<b><i>Objective:</i></b> To report the first case of duloxetine hydrochloride (DH)-induced oral lichenoid drug reaction (OLDR). <b><i>Clinical Presentation and Intervention:</i></b> A 57-year-old male patient presented with painful ulcerative lesions on the bilateral buccal mucosa of 2-year duration.
Nilima S. Kadam +7 more
openaire +3 more sources
Prophylactic use of duloxetine hydrochloride in oxaliplatin-induced first-bite syndrome [PDF]
First-bite syndrome (FBS) is manifested as acute and severe pain in the parotid region occurring at the first bite of a meal. While most cases of FBS arise after surgeries involving the deep lobe of the parotid gland, chemotherapy-induced FBS is extremely rare.
Kensuke Uraguchi +3 more
openaire +3 more sources
Simultaneous measurement of duloxetine hydrochloride and avanafil at dual-wavelength using novel ecologically friendly TLC-densitometric method: application to synthetic mixture and spiked human plasma with evaluation of greenness and blueness [PDF]
The simultaneous assay of duloxetine hydrochloride (DLX) and avanafil (AVN) in their pure forms, synthetic mixtures, and spiked human plasma was achieved using a novel, eco-friendly, sensitive, and specific HPTLC methodology that have been established ...
Sayed M. Derayea +3 more
doaj +2 more sources
A green TLC–densitometric bioanalytical method for concurrent determination of duloxetine and risperidone in human plasma with in-silico DDI evaluation [PDF]
Schizophrenia is a chronic, complex and severs psychiatric disorder that impacts men and women globally. The combined use of atypical antipsychotics; risperidone (RSP), and antidepressants medications; duloxetine hydrochloride (DLX), has grown more ...
Fatma Magdy +2 more
doaj +2 more sources
Development and validation of an analytical method for the stability of duloxetine hydrochloride
AbstractThe objective of the study was to develop and validate an analytical method for estimating the stability of duloxetine hydrochloride. The drug was subjected to the stress conditions prescribed by the International Conference on Harmonization, including hydrolysis, oxidation, photolysis and dry heat.
Datar, Prasanna A., Waghmare, Rohan U.
openaire +3 more sources
Development of Duloxetine Hydrochloride Loaded Mesoporous Silica Nanoparticles: Characterizations and In Vitro Evaluation [PDF]
Ubaidulla U +2 more
exaly +2 more sources
Potent LeuBAT inhibitors designed in silico as next-generation duloxetine analogs for enhanced major depressive disorder treatment [PDF]
Major Depressive Disorder (MDD), a leading global health challenge, urgently requires advanced therapeutics to mitigate its widespread impact. In this study, a series of duloxetine (DLX) analogs were designed and evaluated using a comprehensive in silico
Mehdi Yoosefian +3 more
doaj +2 more sources
Genome-wide association study −Driven drug repositioning for the treatment of insomnia [PDF]
Insomnia is a prevalent sleep disorder characterized by difficulty initiating or maintaining sleep, leading to severe health complications, increased mortality, and substantial socioeconomic burdens.
Rahmat Dani Satria +13 more
doaj +2 more sources
Synergistic combination of duloxetine hydrochloride and fluconazole reduces the cell growth and capsule size of Cryptococcus neoformans [PDF]
This study aimed to evaluate the effect of duloxetine hydrochloride (DH) on Cryptococcus neoformans. DH minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) were 18.5 µg/mL, and the combination with fluconazole (FLZ) reduced ...
RAQUEL T. MENEZES +4 more
doaj +1 more source

