Structure of racemic duloxetine hydrochloride
Acta Crystallographica Section E: Crystallographic Communications, 2023 Duloxetine hydrochloride (trade name Cymbalta) is marketed as a single enantiomer (S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propylaminium chloride, C18H20NOS+·Cl−, which is twice as effective as the (R)-enantiomer in serotonin uptake. Here, we
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Retraction: Disposable screen-printed sensors for determination of Duloxetine Hydrochloride [PDF]
Chemistry Central Journal, 2012 This article [1] is retracted as it contains large amounts of text that have been duplicated from another article previously published in Drug Testing and Analysis [2].
Alarfaj Nawal A +2 more
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Duloxetine hydrochloride [PDF]
Acta Crystallographica Section E, 2009 The title compound [systematic name: N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-aminium chloride], C18H20NOS+·Cl−, was crystallized from 1,4-dioxane.
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Formulation study of duloxetine hydrochloride enteric-coated tablets
SN Applied Sciences, 2023 During storage, duloxetine hydrochloride may have an unexpected cross reaction with enteric coated acrylic resin, which may affect the product quality.
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Potent LeuBAT inhibitors designed in silico as next-generation duloxetine analogs for enhanced major depressive disorder treatment [PDF]
Scientific ReportsMajor Depressive Disorder (MDD), a leading global health challenge, urgently requires advanced therapeutics to mitigate its widespread impact. In this study, a series of duloxetine (DLX) analogs were designed and evaluated using a comprehensive in silico
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مجله دانشکده پزشکی اصفهان, 2018 Background: Peripheral neuropathic pain is a common disorder in patients with diabetes mellitus, which causes significant disability. Various treatments for this disorder have been proposed.
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High-performance liquid chromatography–tandem mass spectrometry for simultaneous determination of 23 antidepressants and active metabolites in human serum and its application in therapeutic drug monitoring [PDF]
Frontiers in PharmacologyIntroductionThe incidence and mortality rate from depression are increasing year by year, and depression has become the main cause of global health loss and disability. Currently, the treatment of depression mainly relies on drug intervention.
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Duloxetine Hydrochloride-Induced Oral Lichenoid Reaction: A Case Report. [PDF]
Med Princ Pract, 2015 <b><i>Objective:</i></b> To report the first case of duloxetine hydrochloride (DH)-induced oral lichenoid drug reaction (OLDR). <b><i>Clinical Presentation and Intervention:</i></b> A 57-year-old male patient presented with painful ulcerative lesions on the bilateral buccal mucosa of 2-year duration.
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Synergistic combination of duloxetine hydrochloride and fluconazole reduces the cell growth and capsule size of Cryptococcus neoformans [PDF]
Anais da Academia Brasileira de Ciências, 2022 This study aimed to evaluate the effect of duloxetine hydrochloride (DH) on Cryptococcus neoformans. DH minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) were 18.5 µg/mL, and the combination with fluconazole (FLZ) reduced ...
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Prophylactic use of duloxetine hydrochloride in oxaliplatin-induced first-bite syndrome. [PDF]
Int Cancer Conf JFirst-bite syndrome (FBS) is manifested as acute and severe pain in the parotid region occurring at the first bite of a meal. While most cases of FBS arise after surgeries involving the deep lobe of the parotid gland, chemotherapy-induced FBS is extremely rare.
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