Results 41 to 50 of about 213,451 (221)
Background Duloxetine is an antidepressant that benefits from a wide range of approval in the elderly population, while its safety for use compared to non-elderly is not clearly assessed.
Jean-Charles Roy +4 more
doaj +1 more source
A new, simple and sensitive spectrophotometric method in ultraviolet region has been developed for the determination of duloxetine hydrochloride in bulk and in pharmaceutical formulations.
Mohammad Yunoos +4 more
doaj +1 more source
N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine
The title compound, C19H21NOS, is an intermediate for the synthesis of duloxetine hydrochloride. In the molecular structure, the thiophene and naphthalene ring systems make a dihedral angle of 87.5°. All bond lengths and angles involving heteroatoms
Jin-Tang Wang +3 more
doaj +1 more source
Duloxetine is the only available agent for the medical treatment of stress urinary incontinence (SUI). In this systematic review, we analyzed the efficacy and safety of duloxetine treatment in women with SUI and stress-predominant mixed urinary ...
Naşide Mangır +5 more
doaj +1 more source
Duloxetine hydrochloride enteric coated pellets were formulated using fluidized bed. Three separate layers, the drug layer, the barrier layer, and the enteric layer, were coated onto the inert core pellets.
D. Shravani +2 more
doaj +1 more source
Duloxetine hydrochloride (DUL) is a BCS class-II antidepressant drug, acting via serotonin and norepinephrine reuptake inhibition. Despite high oral absorption, DUL suffers limited bioavailability due to extensive gastric and first-pass metabolism.
Radwa M.A. Abd-Elal +7 more
doaj +1 more source
Polymorphism and a Metastable Solvate of Duloxetine Hydrochloride
Duloxetine hydrochloride (1) is an important antidepressant that acts as a serotonin and noradrenaline reuptake inhibitor that has only recently been characterized by single-crystal X-ray diffraction.
Anne M. Rich (2070217) +3 more
core +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Pharmacological modulation of the R2 blink reflex was comparable whether responses were elicited using standard patch or concentric electrodes. Across nine studies, noradrenergic and GABAergic interventions produced the most consistent effects, supporting the R2 blink reflex as a sensitive biomarker of trigeminofacial nociceptive processing.
Josh Murphy +5 more
wiley +1 more source
Evaluation of duloxetine for chronic pain conditions
Summary Duloxetine hydrochloride (duloxetine) is used as a nonopioid analgesic for the treatment of certain chronic pain conditions. It is a serotonin and norepinephrine reuptake inhibitor and has been approved in the USA for the management of both ...
Daniel J Walker +2 more
core +1 more source

