Results 41 to 50 of about 3,570 (199)

N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine

Acta Crystallographica Section E, 2008
The title compound, C19H21NOS, is an intermediate for the synthesis of duloxetine hydrochloride. In the molecular structure, the thiophene and naphthalene ring systems make a dihedral angle of 87.5°. All bond lengths and angles involving heteroatoms
Jin-Tang Wang, Lin Yuan, Xiao-Qing Zhang, Xiao Tao   +3 more
doaj   +1 more source

Urodynamic investigation by telemetry in Beagle dogs: validation and effects of oral administration of current urological drugs: a pilot study [PDF]

, 2013
Background Vesico-urethral function may be evaluated in humans and dogs by conventional urodynamic testing (cystometry and urethral pressure profilometry) or by electromyography.
Stéphanie Noël, Laurent Massart, Annick Hamaide   +2 more
core   +1 more source

Duloxetine in the Treatment of Women with Urinary Incontinence: A Systematic Review and Meta-analysis of Efficacy Data from Randomized Controlled Clinical Trials

Journal of Urological Surgery, 2023
Duloxetine is the only available agent for the medical treatment of stress urinary incontinence (SUI). In this systematic review, we analyzed the efficacy and safety of duloxetine treatment in women with SUI and stress-predominant mixed urinary ...
Naşide Mangır, Murat Uçar, Ömer Gülpınar, Cüneyd Özkürkçügil, Oktay Demirkesen, Tufan Tarcan   +5 more
doaj   +1 more source

Differential effects of MDMA and methylphenidate on social cognition [PDF]

, 2014
Social cognition is important in everyday-life social interactions. The social cognitive effects of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and methylphenidate (both used for neuroenhancement and as party drugs) are largely unknown.
Crockett, Molly J., Hysek, Cédric M., Liechti, Matthias E., Quednow, Boris B., Schmid, Yasmin, Simmler, Linda D.   +5 more
core   +1 more source

NGX-4010, a capsaicin 8% patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: integrated analysis of two phase III, randomized, controlled trials [PDF]

, 2013
BACKGROUND HIV-associated distal sensory polyneuropathy (HIV-DSP) is the most frequently reported neurologic complication associated with HIV infection.
Brew, Bruce J, Brown, Stephen, Fisher, Martin, Larbalestier, Nicholas, Moyle, Graeme, Orkin, Chloe, Schifitto, Giovanni, Simpson, David M, Tobias, Jeffrey K, Vanhove, Geertrui F   +9 more
core   +1 more source

Duloxetine hydrochloride induced syndrome of inappropriate antidiuretic hormone secretion in depression treatment： a case report

Sichuan jingshen weisheng
Duloxetine hydrochloride，a serotonin-norepinephrine reuptake inhibitor （SNRIs）， is a commonly used antidepressants. Its mechanism of action involves increasing synaptic monoamine neurotransmitters concentration， leading to antidepressant effects.
Yang Shuting, Fan Ajiao
doaj   +1 more source

Formulation, optimization, in-vivo biodistribution studies and histopathological safety assessment of duloxetine HCl-loaded ultra-elastic nanovesicles for antidepressant effect after intranasal and transdermal delivery

International Journal of Pharmaceutics: X, 2023
Duloxetine hydrochloride (DUL) is a BCS class-II antidepressant drug, acting via serotonin and norepinephrine reuptake inhibition. Despite high oral absorption, DUL suffers limited bioavailability due to extensive gastric and first-pass metabolism.
Radwa M.A. Abd-Elal, Aya M. Essawy, Maha A. Salem, Mahitab Elsayed, Mona G. Khalil, Eman Abdelhakeem, Nouran A. Ali, Mai Ahmed Tawfik   +7 more
doaj   +1 more source

Functioning in patients with major depression treated with duloxetine or a selective serotonin reuptake inhibitor in East Asia [PDF]

, 2016
PURPOSE: To assess and compare the levels of functioning in patients with major depressive disorder treated with either duloxetine with a daily dose of ≤60 mg or a selective serotonin reuptake inhibitor (SSRI) as monotherapy for up to 6 months in a ...
Brugnoli, Roberto, Dueñas, Héctor, Haro Abad, Josep Maria, Hong, Jihyung, Moneta, Maria Victoria, Montgomery, William, Novick, Diego, Yue, Li, Zhu, Gang   +8 more
core   +2 more sources

Estimation of duloxetine hydrochloride in pharmaceutical formulations by RP-HPLC method

Indian Journal of Pharmaceutical Sciences, 2008
Simple, specific, accurate and precise method, namely, reverse phase high performance liquid chromatography was developed for estimation of duloxetine HCl in pharmaceutical formulations. For the high performance liquid chromatography method, Phenomenox C-18, 5 μm column consisting of 250×4.6 mm i.d. in isocratic mode, with mobile phase containing 0.01M
Patel, Sejal K., Patel, N. J., Patel, K. M., Patel, P. U., Patel, B. H.   +4 more
openaire   +3 more sources

Preparation and optimization of various parameters of enteric coated pellets using the Taguchi L9 orthogonal array design and their characterization

Acta Pharmaceutica Sinica B, 2011
Duloxetine hydrochloride enteric coated pellets were formulated using fluidized bed. Three separate layers, the drug layer, the barrier layer, and the enteric layer, were coated onto the inert core pellets.
D. Shravani, P.K. Lakshmi, J. Balasubramaniam   +2 more
doaj   +1 more source