Results 51 to 60 of about 213,451 (221)

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

Chirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu   +1 more
wiley   +1 more source

Formulation and Evaluation of Duloxetine Hydrochloride Delayed Release Capsules [PDF]

, 2013
the present study is to develop and evaluate a delayed release oral capsule comprising Duloxetine Hydrochloride mini tablets 60mg strength with various enteric coating polymers with the following objectives : To study the Drug-Excipient compatibility. To
Pratap, S
core  

A Comparative Study on the Effect of Duloxetine Hydrochloride, Venlafaxine Hydrochloride, and Pregabalin on the Sensory Symptoms in Patients with Diabetic Polyneuropathy

مجله دانشکده پزشکی اصفهان, 2018
Background: Peripheral neuropathic pain is a common disorder in patients with diabetes mellitus, which causes significant disability. Various treatments for this disorder have been proposed.
Naeimeh Kardanpour, Fariborz Khorvash, Farzin Khorvash, Mohammad Memarzadeh   +3 more
doaj   +1 more source

Curative effect of oxycodone sustained-release tablets combined with duloxetine versus paroxetine in treatment of depression and pain from advanced cancer

Di-san junyi daxue xuebao, 2020
Objective To investigate the efficacy and safety of oxycodone sustained-release tablets combined with different types of antidepressants (duloxetine and paroxetine) in the patients suffering from depression and pain due to advanced cancer.
ZENG Yuan, SUN Jianhai
doaj   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

The Journal of Physiology, Volume 604, Issue 13, Page 5629-5662, 1 July 2026.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite, Xin Zhou, Andreas Koschinski, Wan‐Hua Hong, Marilù Casini, Manuel Koch, Ursula Ravens, Remi Peyronnet, Manuela Zaccolo, Blanca Rodriguez   +9 more
wiley   +1 more source

ECO-FRIENDLY NON-DERIVATIZED HPLC APPROACH FOR SIMULTANEOUS DETERMINATION OF PREGABALIN, MILNACIPRAN, AND DULOXETINE EMPLOYED IN FIBROMYALGIA TREATMENT [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University
A novel, eco-friendly high performance liquid chromatography (HPLC) method was developed for the simultaneous determination of pregabalin (PRE), milnacipran hydrochloride (MIL), and duloxetine hydrochloride (DLU), FDA-approved fibromyalgia drugs.
‪Hussein Ghanem‬‏, Asmaa El- Zaher, Enas Abdelhamed, Sally Tarek Mahmoud   +3 more
doaj   +1 more source

Formulation and Evaluation of Enteric Coated Tablets of Duloxetine Hydrochloride [PDF]

, 2018
A total of five formulations (F-I to F-V) of Duloxetine hydrochloride tablets were developed by direct compression method. The work was carried out to delay the release of Duloxetine hydrochloride by using enteric polymer. From all the above observation
Meeranmydeen, I
core  

Estimation of duloxetine hydrochloride in pharmaceutical formulations by RP-HPLC method

Indian Journal of Pharmaceutical Sciences, 2008
Simple, specific, accurate and precise method, namely, reverse phase high performance liquid chromatography was developed for estimation of duloxetine HCl in pharmaceutical formulations. For the high performance liquid chromatography method, Phenomenox C-18, 5 μm column consisting of 250×4.6 mm i.d. in isocratic mode, with mobile phase containing 0.01M
Patel, Sejal K., Patel, N. J., Patel, K. M., Patel, P. U., Patel, B. H.   +4 more
openaire   +3 more sources

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Stability-Indicating HPTLC Method for Determination of Duloxetine Hydrochloride in Bulk Drug and Tablet Formulation [PDF]

, 2011
A simple, accurate, precise, sensitive, selective, and stability-indicating high-performance thin-layer chromatographic method was developed and validated for determination of duloxetine hydrochloride both in bulk drug as well as in tablet formulation ...
Vandana Arora, Sheikh Shahnawaz, Abdul Wadood Siddiqui, Mir Tariq Masroor   +3 more
core   +1 more source