Comparative effectiveness of dual-action versus single-action antidepressants for the treatment of depression in people living with HIV/AIDS [PDF]
, 2017 Background Depression is the most common psychiatric comorbidity among people living with HIV/AIDS (PLWHA). Little is known about the comparative effectiveness between different types of antidepressants used to treat depression in this population.
Bengston, Angela M. +7 more
core +2 more sources
BMC Neurology, 2008 Background Duloxetine hydrochloride is a reuptake inhibitor of 5-hydroxytryptamine and norepinephrine used to treat depression, generalized anxiety disorder, neuropathic pain, and stress incontinence in women.
Derry Sheena +3 more
doaj +1 more source
A brief review of the pharmacology of amitriptyline and clinical outcomes in treating fibromyalgia [PDF]
, 2017 Fibromyalgia is a complex chronic condition characterized by pain, physical fatigue, sleep disorder and cognitive impairment. Evidence-based guidelines recommend antidepressants as treatments of fibromyalgia where tricyclics are often considered to have ...
Azad +12 more
core +2 more sources
Electrochemical determination of duloxetine hydrochloride at gold electrode [PDF]
, 2022 Duloxetine hydrochloride ( D U L ) , a naphth) I ether amine, inhibits the uptake of serotonin and norepinephrine. The electrochemical behavior of D U L was determined by cyclic voltammetry ( C V ) in phosphate buffer solution at gold electrode by varying pH and scan rate. The electroanalytical application was studied with the aid of differential pulse
Lović, Jelena +5 more
openaire
Prevalence and patterns of antidepressant switching amongst Primary Care patients in the UK [PDF]
, 2017 Objective: Non-response to antidepressant treatment is a substantial problem in primary care, and many patients with depression require additional second-line treatments. This study aimed to examine the prevalence and patterns of antidepressant switching
Gunnell, David +5 more
core +2 more sources
Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives [PDF]
, 2014 Aminoindanes, piperazines, and pipradrol derivatives are novel psychoactive substances found in "Ecstasy" tablets as replacements for 3,4-methylenedioxymethamphetamine (MDMA) or substances sold as "ivory wave." The pharmacology of these MDMA- and ...
Hoener, Marius C. +4 more
core +1 more source
Formulation and characterization of ternary complex of poorly soluble duloxetine hydrochloride [PDF]
Journal of Applied Pharmaceutical Science, 2015 Duloxetine hydrochloride (DXH) suffers from poor solubility and thereby poor absorption, which ultimately leads to poor bioavailability. In present study, an attempt has been made to formulate and characterize duloxetine hydrochloride (DXH) complex, using β-cyclodextrin (β-CD) and different hydrophilic polymers in order to enhance its solubility and ...
Pinakin Pandya +3 more
openaire +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite +9 more
wiley +1 more source
Acute Effects of 3,4-Methylenedioxymethamphetamine and Methylphenidate on Circulating Steroid Levels in Healthy Subjects [PDF]
, 2014 3,4-Methylenedioxymethamphetamine (MDMA, 'ecstasy') and methylphenidate are widely used psychoactive substances. MDMA primarily enhances serotonergic neurotransmission, and methylphenidate increases dopamine but has no serotonergic effects.
Hysek, Cédric M. +6 more
core +1 more source
Nanochanneled Device and Related Methods [PDF]
, 2013 A capsule configured for in vivo refilling of a therapeutic agent.
Ferrari, Mauro +4 more
core +5 more sources