Results 31 to 40 of about 1,894 (158)

Simple UV Spectrophotometric Determination of Duloxetine Hydrochloride in Bulk and in Pharmaceutical Formulations

E-Journal of Chemistry, 2010
A new, simple and sensitive spectrophotometric method in ultraviolet region has been developed for the determination of duloxetine hydrochloride in bulk and in pharmaceutical formulations.
Mohammad Yunoos, D. Gowri Sankar, B. Pragati Kumar, Shahul Hameed, Azmath Hussain   +4 more
doaj   +1 more source

N,N-Dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine

Acta Crystallographica Section E, 2008
The title compound, C19H21NOS, is an intermediate for the synthesis of duloxetine hydrochloride. In the molecular structure, the thiophene and naphthalene ring systems make a dihedral angle of 87.5°. All bond lengths and angles involving heteroatoms
Jin-Tang Wang, Lin Yuan, Xiao-Qing Zhang, Xiao Tao   +3 more
doaj   +1 more source

Tolerability of duloxetine in elderly and in non-elderly adults: a protocol of a systematic review and individual participant data meta-analysis of randomized placebo-controlled trials

Systematic Reviews, 2022
Background Duloxetine is an antidepressant that benefits from a wide range of approval in the elderly population, while its safety for use compared to non-elderly is not clearly assessed.
Jean-Charles Roy, Chloé Rousseau, Alexis Jutel, Florian Naudet, Gabriel Robert   +4 more
doaj   +1 more source

DULOXETINE HYDROCHLORIDE INDUCED PARESTHESIA - A CASE REPORT

Asian Journal of Pharmaceutical and Clinical Research, 2023
A 45-year-old HIV-positive female patient experienced a generalized burning sensation after the administration of one dose of duloxetine 20 mg. The patient’s concurrent medications include a fixed drug combination of nevirapine 200 mg, Lamivudine 150 mg, and Zidovudine 300 mg, twice daily for 5 years.
SAI PAWAN AR, Birendra Srivastava, Ramesh Adepu   +2 more
openaire   +1 more source

Duloxetine in the Treatment of Women with Urinary Incontinence: A Systematic Review and Meta-analysis of Efficacy Data from Randomized Controlled Clinical Trials

Journal of Urological Surgery, 2023
Duloxetine is the only available agent for the medical treatment of stress urinary incontinence (SUI). In this systematic review, we analyzed the efficacy and safety of duloxetine treatment in women with SUI and stress-predominant mixed urinary ...
Naşide Mangır, Murat Uçar, Ömer Gülpınar, Cüneyd Özkürkçügil, Oktay Demirkesen, Tufan Tarcan   +5 more
doaj   +1 more source

Duloxetine hydrochloride induced syndrome of inappropriate antidiuretic hormone secretion in depression treatment： a case report

Sichuan jingshen weisheng
Duloxetine hydrochloride，a serotonin-norepinephrine reuptake inhibitor （SNRIs）， is a commonly used antidepressants. Its mechanism of action involves increasing synaptic monoamine neurotransmitters concentration， leading to antidepressant effects.
Yang Shuting, Fan Ajiao
doaj   +1 more source

Preparation and optimization of various parameters of enteric coated pellets using the Taguchi L9 orthogonal array design and their characterization

Acta Pharmaceutica Sinica B, 2011
Duloxetine hydrochloride enteric coated pellets were formulated using fluidized bed. Three separate layers, the drug layer, the barrier layer, and the enteric layer, were coated onto the inert core pellets.
D. Shravani, P.K. Lakshmi, J. Balasubramaniam   +2 more
doaj   +1 more source

Formulation, optimization, in-vivo biodistribution studies and histopathological safety assessment of duloxetine HCl-loaded ultra-elastic nanovesicles for antidepressant effect after intranasal and transdermal delivery

International Journal of Pharmaceutics: X, 2023
Duloxetine hydrochloride (DUL) is a BCS class-II antidepressant drug, acting via serotonin and norepinephrine reuptake inhibition. Despite high oral absorption, DUL suffers limited bioavailability due to extensive gastric and first-pass metabolism.
Radwa M.A. Abd-Elal, Aya M. Essawy, Maha A. Salem, Mahitab Elsayed, Mona G. Khalil, Eman Abdelhakeem, Nouran A. Ali, Mai Ahmed Tawfik   +7 more
doaj   +1 more source

Duloxetine for painful diabetic neuropathy and fibromyalgia pain: systematic review of randomised trials

BMC Neurology, 2008
Background Duloxetine hydrochloride is a reuptake inhibitor of 5-hydroxytryptamine and norepinephrine used to treat depression, generalized anxiety disorder, neuropathic pain, and stress incontinence in women.
Derry Sheena, Gaskell Helen, Sultan Asquad, Moore R Andrew   +3 more
doaj   +1 more source

Pharmacological Influences on the R2 Blink Reflex Response in Healthy Participants: A Systematic Review

European Journal of Neuroscience, Volume 64, Issue 3, August 2026.
Pharmacological modulation of the R2 blink reflex was comparable whether responses were elicited using standard patch or concentric electrodes. Across nine studies, noradrenergic and GABAergic interventions produced the most consistent effects, supporting the R2 blink reflex as a sensitive biomarker of trigeminofacial nociceptive processing.
Josh Murphy, Joy Krecke, Celia Morgan, Paul H. Strutton, Kirsty Bannister, Sam W. Hughes   +5 more
wiley   +1 more source