Results 31 to 40 of about 19,922 (207)

Effect of duloxetine on neuropathic pain in patients intolerant to continuous administration of pregabalin

Spine Surgery and Related Research, 2017
Purpose: We examined duloxetine's effectiveness in the treatment of neuropathic pain in patients who were intolerant to continuous pregabalin administration.
Yohei Shimada, Kazuhide Inage, Sumihisa Orita, Masao Koda, Kazuyo Yamauchi, Takeo Furuya, Junichi Nakamura, Miyako Suzuki, Kazuki Fujimoto, Yasuhiro Shiga, Koki Abe, Hirohito Kanamoto, Masahiro Inoue, Hideyuki Kinoshita, Masaki Norimoto, Tomotaka Umimura, Kazuhisa Takahashi, Seiji Ohtori   +17 more
doaj   +1 more source

Pharmacokinetics of duloxetine self-administered in overdose with quetiapine and other antipsychotic drugs in a Japanese patient admitted to hospital

Journal of Pharmaceutical Health Care and Sciences, 2021
Background Combinations of antidepressant duloxetine (at doses of 40–60 mg/day) and other antipsychotics are frequently used in clinical treatment; however, several fatal and nonfatal cases of duloxetine overdose have been documented.
Koichiro Adachi, Satoru Beppu, Kei Nishiyama, Makiko Shimizu, Hiroshi Yamazaki   +4 more
doaj   +1 more source

The Microglial Activation Inhibitor Minocycline, Used Alone and in Combination with Duloxetine, Attenuates Pain Caused by Oxaliplatin in Mice

Molecules, 2021
The antitumor drug, oxaliplatin, induces neuropathic pain, which is resistant to available analgesics, and novel mechanism-based therapies are being evaluated for this debilitating condition.
Kinga Sałat, Anna Furgała-Wojas, Robert Sałat   +2 more
doaj   +1 more source

Importance of anogenital distance parameters on duloxetine success in women with stress urinary incontinence

Ginekologia Polska
OBJECTIVES: To clarify the impact of anogenital distance (AGD) on duloxetine success in the management of women with stress urinary incontinence (SUI). MATERIAL AND METHODS: Patients who have been diagnosed with SUI, were evaluated for inclusion in the ...
Mazhar Ortac, M. Firat Ozervarli, Ufuk Caglar, Resat Aydin, Senol Tonyali, Omer Sarilar, Faruk Ozgor   +6 more
doaj   +1 more source

Duloxetine reduces pain after Total hip arthroplasty: a prospective, randomized controlled study

BMC Musculoskeletal Disorders, 2021
Background Previous studies have demonstrated the efficacy of duloxetine in reducing postoperative pain and opioid consumption. However, the effect of duloxetine on total hip arthroplasty (THA) remains unclear.
Hao Li, Wei-Nan Zeng, Zi-Chuan Ding, Ming-Cheng Yuan, Yong-Rui Cai, Zong-Ke Zhou   +5 more
doaj   +1 more source

A scoping review of adverse events associated with concomitant beta‐adrenoreceptor blockers and selective serotonin reuptake inhibitors

British Journal of Clinical Pharmacology, EarlyView.
Beta‐adrenoreceptor blockers (beta‐blockers) and selective serotonin reuptake inhibitors (SSRIs) are commonly used medications and often used together, such as for the treatment of anxiety. However, there is no recent review of any potential adverse events related to concomitant use of medicines from each group.
Ziyi Cai, James Sutton, Charlotte Archer, Caroline S. Copeland, Joseph Hayes, Charles E. Leonard, Nicky Lidbetter, Kenneth K. C. Man, Faraz Mughal, Ian C. K. Wong, Hayley C. Gorton   +10 more
wiley   +1 more source

Evaluation of analgesic and anti-inflammatory activity of ibuprofen and duloxetine in animal models

National Journal of Physiology, Pharmacy and Pharmacology, 2019
Background: Several antidepressants are currently being used as analgesic in neuropathic pain, but their effect on inflammatory pain is not clear. Few studies have shown that duloxetine also has anti-inflammatory effect along with its antinociceptive ...
Tushar Dhawale, Subodh Kumar, Dharmadhikari S   +2 more
doaj   +1 more source

Medication Use During Breastfeeding—An Understudied Population: A Five‐Year Experience in the Pharmacovigilance Center of Lyon

Clinical Pharmacology &Therapeutics, EarlyView.
Medication use during breastfeeding is common, yet data on drug transfer into breast milk and infant exposure remain limited. This study describes real‐world requests concerning medication compatibility with breastfeeding managed by the Lyon pharmacovigilance center over five years.
Blandine Bertin, Aurore Gouraud, Anthony Facile, Fanny Ledys, Sabrina Pierre, Véronique Pizzoglio, Thierry Vial, Marine Auffret, Marina Atzenhoffer   +8 more
wiley   +1 more source

Response to duloxetine in chronic low back pain: exploratory post hoc analysis of a Japanese Phase III randomized study [PDF]

, 2017
Toshinaga Tsuji,1 Naohiro Itoh,1 Mitsuhiro Ishida,2 Toshimitsu Ochiai,3 Shinichi Konno4 1Medical Affairs Department, 2Clinical Research Development, 3Biostatistics Department, Shionogi & Co.
Konno S, Toshimitsu Ochiai, Tsuji T, Ochiai T, Naohiro Itoh, Ishida M, Itoh N, Toshinaga Tsuji, Shin-ichi Konno, Mitsuhiro Ishida   +9 more
core   +1 more source

Population‐Stratified Distributions of Post‐Mortem Blood Drug Concentrations: An Epidemiological Framework for Contextual Interpretation

Drug Testing and Analysis, EarlyView.
Post‐mortem blood drug concentrations exhibit substantial overlap between deaths in which a drug was implicated and those in which it was not. Analysis of over 58,000 NPSUM cases demonstrates that demographic stratification does not resolve this uncertainty, reinforcing the need for contextual, evidence‐based interpretation rather than concentration ...
Thikra Algahtani, Kirsten L. Rock, Kathleen Rice‐Davies, Rebecca Lo, Benedict Morley, Stephen Morley, Caroline S. Copeland   +6 more
wiley   +1 more source