Results 111 to 120 of about 1,894 (158)

Aromatase inhibitors induce pain-like musculoskeletal symptoms in mice: behavioural, pharmacological and pathophysiological characterization. [PDF]

open access: yesBr J Pharmacol
Caillaud M   +14 more
europepmc   +1 more source

Study on fluorescence characteristics of duloxetine hydrochloride

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2008
The fluorescence characteristics of duloxetine hydrochloride are studied in this paper. The fluorescence emission spectra of duloxetine demonstrate that intramolecular charge-transfer takes place between thiophene ring and napthalenyloxy group upon irradiation.
Xiangping, Liu   +2 more
openaire   +4 more sources

Polymorphism and a Metastable Solvate of Duloxetine Hydrochloride

Molecular Pharmaceutics, 2011
Duloxetine hydrochloride (1) is an important antidepressant that acts as a serotonin and noradrenaline reuptake inhibitor that has only recently been characterized by single-crystal X-ray diffraction. This study describes an investigation into polymorphism of duloxetine hydrochloride, discusses the challenges of characterizing new structures, and ...
Christopher E, Marjo   +3 more
openaire   +4 more sources

Study on the binding of chiral drug duloxetine hydrochloride to human serum albumin☆

European Journal of Medicinal Chemistry, 2010
Duloxetine holds a special promise as an antidepressant, and its effect depends on its binding to human serum albumin (HSA). For this reason, the binding mechanism of duloxetine with HSA was investigated. The specific binding site in HSA was identified and binding constants were determined.
Xiangping, Liu, Yingxiang, Du
openaire   +4 more sources

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