Results 91 to 100 of about 213,451 (221)

Duloxetine increased MDMA exposure.

, 2012
Pharmacokinetics of MDMA, MDA, HMMA, and duloxetine (a–d). Duloxetine was administered 16 h and 4 h before MDMA, which was administered at the 0 h time point. Duloxetine increased the Cmax and AUC0–6 of MDMA (a), had no significant effect on MDA exposure
Marius C. Hoener (166578), Cédric M. Hysek (166535), Linda D. Simmler (166540), Massimiliano Donzelli (166552), Valentina G. Nicola (166543), Stephan Krähenbühl (166557), Nerina Vischer (166548), Jörg Huwyler (166572), Eric Grouzmann (166564), Matthias E. Liechti (166584)   +9 more
core   +1 more source

REVERSE PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY (RP-HPLC) METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF SILDENAFIL CITRATE AND DULOXETINE HYDROCHLORIDE IN COMBINE DOSAGE FORM [PDF]

Sildenafil citrate (SIL) and Duloxetine (DULO) is a combination, which is a serotoninnorepinephrine reuptake inhibitor (SNRI). The primary goal of the endeavor is to develop and evaluate a stability-indicating reverse-phase liquid chromatography (RP-HPLC)
Vyasa, Mudra, Parikh, Nisha, Doshi, Miral   +2 more
core  

Duloxetine in the treatment of generalized anxiety disorder

, 2009
Alan Wright, Chad VanDenBergCenter for Clinical Research, Mercer University, Atlanta, GA, USAAbstract: Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) which is FDA approved for the treatment of generalized anxiety disorder (GAD) in ...
Chad VanDenBerg, Alan Wright
core  

Duloxetine in the treatment of chronic pain due to fibromyalgia and diabetic neuropathy

, 2010
Alan Wright, Kyle E Luedtke, Chad VanDenBergCenter for Clinical Research, Mercer University, Atlanta, Georgia, USAAbstract: Duloxetine is a serotonin-norepinephrine reuptake inhibitor approved by the US Food and Drug Administration for the treatment of ...
null Wright, Kyle E Luedtke, Chad VanDenBerg, Alan Wright   +3 more
core   +1 more source

Antidepressants for pain management in adults with chronic pain: a network meta-analysis

Health Technology Assessment
Background Chronic pain is common and costly. Antidepressants are prescribed to reduce pain. However, there has not been a network meta-analysis examining all antidepressants across all chronic pain conditions, so effectiveness and safety for most ...
Hollie Birkinshaw, Claire Friedrich, Peter Cole, Christopher Eccleston, Marc Serfaty, Gavin Stewart, Simon White, Andrew Moore, David Phillippo, Tamar Pincus   +9 more
doaj   +1 more source

Synthesis of Deuterium-Labelled (±)-Duloxetine-d₅ as an Internal Standard

, 2018
The synthesis of (±)-duloxetine- d6, which is needed for metabolism studies, has been achieved in four steps. The product of a Mannich reaction of 2-acetylthiophene, dimethylamine- d6 hydrochloride and paraformaldehyde- d2 was reduced with NaBH4 to ...
Yueqiu Wang, Dawei Liang, Ye Yuan, Bin Zhang   +3 more
core   +1 more source

DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR THE DETERMINATION OF DULOXETINE HYDROCHLORIDE IN PHARMACEUTICAL DOSAGE FORM

International Journal of Biology Pharmacy and Allied Sciences, 2023

semanticscholar   +1 more source

Suicidality during treatment with serotonin and norepinephrine reuptake inhibitors

European Psychiatry
Introduction Treatment choice when prescribing antidepressants for major depressive disorder (MDD) is often influenced by safety and tolerability profiles.
I. Da Fonseca Pinto, A. Elias de Sousa, M. A. Vieira-Coelho   +2 more
doaj   +1 more source

Comparative pain and mood effects in patients with comorbid fibromyalgia and major depressive disorder: Secondary analyses of four pooled randomized controlled trials of duloxetine

, 2011
The objective of this paper is to better understand the relationship of pain and mood in patients with fibromyalgia and comorbid major depressive disorder (MDD).
Choy, Ernest, Clauw, Daniel J., Bradley, Laurence, Lauren B. Marangell, Madelaine M. Wohlreich, Daniel J. Clauw, Wohlreich, Madelaine M., Ernest Choy, Laurence Bradley, Shoemaker, Scarlett, Marangell, Lauren B., Wang, Fujun, Philip Mease, Fujun Wang, Scarlett Shoemaker, Mease, Philip   +15 more
core   +1 more source

Update on duloxetine for the management of stress urinary incontinence

, 2008
Maya Basu, Jonathan RA DuckettDepartment of Obstetrics and Gynaecology, Medway Maritime Hospital, Gillingham, Kent, UKAbstract: Duloxetine is a relatively balanced serotonin and noradrenaline reuptake inhibitor (SNRI), which is the first drug with widely
Maya Basu, Jonathan RA Duckett
core