Results 91 to 100 of about 3,570 (199)

Medication Causes and Treatment of Delirium in Patients With and Without Dementia

Brain and Behavior, Volume 15, Issue 7, July 2025.
Medication associated risk related to cause and treatment of delirium ABSTRACT Introduction Medication associated with delirium in adult patients is poorly understood and considered both a predisposing and precipitating factor. Prescribing advice is lacking. This systematic review aims to collate evidence on medication risks in delirium associated with
Anita Elaine Weidmann, Rut Matthíasdóttir, Guðný Björk Proppé, Ivana Tadić, Pétur Sigurdur Gunnarsson, Freyja Jónsdóttir   +5 more
wiley   +1 more source

TRIPS implementation and secondary pharmaceutical patenting in Brazil and India [PDF]

, 1978
This article compares national approaches toward secondary pharmaceutical patents. Because secondary patents can extend periods of exclusivity and delay generic competition, they can raise prices and reduce access to medicines. Little is known about what
Bhaven N. Sampat, Kenneth C. Shadlen, T Amin, M Basso, ER Berndt, P Drahos, P Drahos, R Falvey, R Falvey, J Farrell, KM Gopakumar, CS Hemphill, CS Hemphill, CS Hemphill, L Howard, O Ivus, A Kapczynski, A Kapczynski, VYM Kunisawa, MK Kyle, S La Croix, M Lemley, M Liu, J-F Morin, WG Park, Y Qian, BN Sampat, FM Scherer, A Sengupta, KC Shadlen, KC Shadlen, CM Sweet, N Vernaz   +32 more
core   +1 more source

The Interplay of Cross‐Organ Immune Regulation in Inflammation and Cancer

MedComm, Volume 6, Issue 7, July 2025.
Organs interact dynamically through immune regulation, influencing systemic immune responses and disease progression. We review molecular and cellular mechanisms of cross‐organ immune regulation in inflammation and cancer, focusing on gut, liver, and brain interactions with other organs.
Jie Dou, Jinzuo Jiang, Yangtao Xue, Xiaoqi Jiang, Yongzhuo Jiang, Peng Xiao, Junjie Xu   +6 more
wiley   +1 more source

DESIGN AND IN VITRO CHARACTERIZATION OF MUCOADHESIVE BUCCAL PATCHES OF DULOXETINE HYDROCHLORIDE

International Journal of Pharmacy and Pharmaceutical Sciences, 2017
<p><strong>Objective: </strong>Buccal mucosa is a potential site for the delivery of drugs to the systemic circulation, a drug administered through the buccal mucosa enters directly to the systemic circulation, thereby which bypass the drug from the first-pass hepatic metabolism and adverse gastrointestinal effect.
Himabindu Peddapalli, Krishna Mohan Chinnala, Nagaraj Banala   +2 more
openaire   +2 more sources

Evaluating the Effect of Preoperative Duloxetine Administration on Postoperative Pain in Patients under Abdominal Hysterectomy

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2020
BACKGROUND AND OBJECTIVE: Postoperative pain management is considered as a part of recovery. Duloxetine (DLX), an anti-depressant medication, is a possible choice for the multimodal anesthetic strategy.
H Sattari, M Noroozi, M Hashemian, MR Doroodian, F Mansoori Nasab   +4 more
doaj  

Subchronic vortioxetine enhances cortical activity [PDF]

, 2016
Vortioxetine (VOR) is a multimodal antidepressant drug. VOR is a 5-HT3-R, 5-HT7-R and 5-HT1D-R antagonist, 5-HT1B-R partial agonist, 5-HT1A-R agonist, and serotonin transporter (SERT) inhibitor.
Artigas, Francesc, Celada, Pau, Riga, Maurizio, Sánchez, Connie, Teruel-Martí, Vicent   +4 more
core   +1 more source

The Nasal–Brain Drug Delivery Route: Mechanisms and Applications to Central Nervous System Diseases

MedComm, Volume 6, Issue 6, June 2025.
Τhe BBB restricts CNS drug delivery. NBDD bypasses the BBB via olfactory/trigeminal routes, enabling CNS delivery of therapeutic (small molecules, biologics, nucleic acids) for neurodegenerative/psychiatric disorders and brain tumors using advanced NBDD delivery systems (e.g nanocarriers) to enhance targeting and bioavailability.
Yi Qiu, Shiyuan Huang, Li Peng, Li Yang, Guosong Zhang, Tao Liu, Fang Yan, Xi Peng   +7 more
wiley   +1 more source

Comparison of the Efficacy of Duloxetine Versus Pregabalin for Pain Relief of Neuropathy in Diabetics

Pakistan Journal of Medicine and Dentistry
Background: Neuropathy is a common complication in diabetic patients with clinical manifestations of feet and hands paresthesia, pain in the lower legs, and a burning sensation in the soles. A wide variety of medications are used for diabetic neuropathy
Hamid Raza Gulzar, Nosheen Zahoor, Ambreen Zahoor, Hina Saghir, Mariam Tariq, Asma Bibi   +5 more
doaj   +1 more source

Functional Outcomes of Thoracolumbar Junction Spine Fractures [PDF]

, 2019
Introduction. Few studies have evaluated the functionaloutcomes of traumatic thoracic and lumbar vertebral bodyfractures. This study evaluated the functional and clinicaloutcomes of patients, who sustained a fracture to thethoracolumbar area of the spine
Carr-Maben, Catherine L., Chong, Alexander CM., Jones, Teresa L., Moskowitz, Alan, Stuckey, Ryan M., Wall, Bradford A., Whitaker, M. Camden   +6 more
core   +2 more sources

Concomitant Use of Etrasimod With Opioids or Antidepressants in Patients With Ulcerative Colitis—A Safety Analysis

United European Gastroenterology Journal, Volume 13, Issue 5, Page 719-727, June 2025.
ABSTRACT Background Etrasimod is an oral, once‐daily (q.d.), selective sphingosine 1‐phosphate (S1P)1,4,5 receptor modulator for the treatment of moderately to severely active ulcerative colitis (UC). Unlike the S1P receptor modulator ozanimod, etrasimod does not have a molecular structure to inhibit monoamine oxidase (MAO).
Anita Afzali, Miguel Regueiro, Andres J. Yarur, Yamile Zabana, Siew C. Ng, Sujatha Menon, Aoibhinn McDonnell, Krisztina Lazin, Michael Keating, Abhishek Bhattacharjee, Diogo Branquinho, Eustratios Bananis, Laurent Peyrin‐Biroulet   +12 more
wiley   +1 more source