Results 101 to 110 of about 213,451 (221)

Genome-wide association study −Driven drug repositioning for the treatment of insomnia

Journal of Genetic Engineering and Biotechnology
Insomnia is a prevalent sleep disorder characterized by difficulty initiating or maintaining sleep, leading to severe health complications, increased mortality, and substantial socioeconomic burdens.
Rahmat Dani Satria, Wirawan Adikusuma, Usi Sukorini, Devy Eka Avitasari, Indra Sari Kusuma Harahap, Mohammad Hendra Setia Lesmana, Lalu Muhammad Irham, Nur Imma Fatimah Harahap, Pranindya Rinastiti, Donytra Arby Wardhana, Richardus Wisnandito Prabasaktya, Chiou-Feng Lin, Aprilia Paramitasari, Andrian Fajar Kusumadewi   +13 more
doaj   +1 more source

IMPLEMENTATION OF QBD APPROACH TO DEVELOP AND VALIDATE ANALYTICAL METHOD FOR SIMULTANEOUS ESTIMATION OF DULOXETINE HYDROCHLORIDE AND METHYLCOBALAMIN IN PHARMACEUTICAL DOSAGE FORM BY HPTLC METHOD [PDF]

, 2016
Objective: To develop and validate High-Performance Thin Layer Chromatography (HPTLC) analytical method for the determination of Duloxetine Hydrochloride (DUL) and Methylcobalamin (MEC) in the standard mixture and pharmaceutical capsule dosage form by ...
Patel, Bhavesh, Sheladia, Seema
core   +1 more source

UEG Week 2025 Poster Presentations

United European Gastroenterology Journal, Volume 13, Issue S8, Page S803-S1476, October 2025.
wiley   +1 more source

Simultaneous quantification of duloxetine and 1-naphthol in pharmaceutical and biological matrices using a sensitive and eco-friendly synchronous fluorescence technique

Beni-Suef University Journal of Basic and Applied Sciences
Background Duloxetine hydrochloride (DL) is a widely prescribed serotonin–norepinephrine reuptake inhibitor requiring stringent quality control due to the potential presence of 1-naphthol (NP), a genotoxic process-related impurity.
Fatma F. Abdallah, Aly M. Waseem, Ali M. Yehia, Nehal F. Farid   +3 more
doaj   +1 more source

Duloxetine in the management of diabetic peripheral neuropathic pain

, 2011
Michelle J Ormseth, Beth A Sholz, Chad S BoomershineDivision of Rheumatology and Immunology, Vanderbilt University, Nashville, TN, USAAbstract: Diabetic neuropathy affects up to 70% of diabetics, and diabetic peripheral neuropathic pain (DPNP) is the ...
Ormseth MJ, Scholz BA, Boomershine CS
core  

Predictors of duloxetine adherence and persistence in patients with fibromyalgia

, 2012
Zhanglin Cui, Yang Zhao, Diego Novick, Douglas FariesEli Lilly and Company, Indianapolis, IN, USAObjectives: Adherence to medication for the treatment of fibromyalgia (FM) is predictive of lower overall health-care costs, and thus a lower burden on both ...
Novick D, Cui Z, Faries D, Zhao Y
core  

Cymbalta [PDF]

, 2013
Poster outlines the chemical make-up and uses of Cymbalta (Duloxetine Hydrochloride) which is used to treat major depression, generalized anxiety, fibromyalgia, and diabetic neuropathy.
Elder, Ryann S.
core  

High-performance liquid chromatography–tandem mass spectrometry for simultaneous determination of 23 antidepressants and active metabolites in human serum and its application in therapeutic drug monitoring

Frontiers in Pharmacology
IntroductionThe incidence and mortality rate from depression are increasing year by year, and depression has become the main cause of global health loss and disability. Currently, the treatment of depression mainly relies on drug intervention.
Jinglong Wang, Junjie Wang, Chenxiao Zhang, Guofei Li   +3 more
doaj   +1 more source

Duloxetine for the treatment of generalized anxiety disorder: a review

, 2008
Ahsan Y Khan, Matthew MacalusoDepartment of Psychiatry and Behavioral Sciences, University of Kansas School of Medicine-Wichita, Wichita, KS, USAAbstract: Approximately 16 million people in the United States suffer from anxiety disorders alone, while ...
Ahsan Y Khan, Matthew Macaluso
core  

Potent LeuBAT inhibitors designed in silico as next-generation duloxetine analogs for enhanced major depressive disorder treatment

Scientific Reports
Major Depressive Disorder (MDD), a leading global health challenge, urgently requires advanced therapeutics to mitigate its widespread impact. In this study, a series of duloxetine (DLX) analogs were designed and evaluated using a comprehensive in silico
Mehdi Yoosefian, Hedieh Bayramzadeh, Kasim Sakran Abass, Tahmineh Mokhtari   +3 more
doaj   +1 more source