TREatment of ATopic eczema (TREAT) Registry Taskforce: consensus on how and when to measure the core dataset for atopic eczema treatment research registries. [PDF]
, 2019 BackgroundComparative, real-life and long-term evidence on the effectiveness and safety of phototherapy and systemic therapy in moderate-to-severe atopic eczema (AE) is limited.
Apfelbacher, CJ +17 more
core
Antidepressant activity of anti-cytokine treatment: a systematic review and meta-analysis of clinical trials of chronic inflammatory conditions. [PDF]
, 2018 Inflammatory cytokines are commonly elevated in acute depression and are associated with resistance to monoaminergic treatment. To examine the potential role of cytokines in the pathogenesis and treatment of depression, we carried out a systematic review
A Hinz +76 more
core +1 more source
JEADV Clinical Practice, EarlyView.We present a case of a 31‐year‐old female with alopecia universalis, psoriasis vulgaris, and psoriatic arthritis, who showed poor response to prior treatments. Following the initiation of a combination therapy with tofacitinib and methotrexate, significant improvements in joint pain and hair regrowth were observed.
Jan Nicolai Wagner +4 more
wiley +1 more source
Journal of Cutaneous Immunology and Allergy, 2022 Dupilumab demonstrated high efficacy and tolerable safety profiles in moderate‐to‐severe atopic dermatitis (AD) patients in clinical trials; however, certain patients suffer from facial redness, while obtaining good responses on the trunk and limbs to ...
Hideaki Uchida +10 more
doaj +1 more source
Precision Medicine in Targeted Therapies for Severe Asthma:Is There Any Place for "omics" Technology? [PDF]
, 2018 According to the current guidelines, severe asthma still represents a controversial topic in terms of definition and management. The introduction of novel biological therapies as a treatment option for severe asthmatic patients paved the way to a ...
Bertolini, Francesca +6 more
core +2 more sources
JEADV Clinical Practice, EarlyView.ABSTRACT The treatment landscape for moderate‐to‐severe atopic dermatitis (AD) has evolved significantly with the introduction of novel targeted therapies addressing specific pathogenic mechanisms of the disease. Despite this therapeutic revolution, a proportion of patients experience intolerance and/or inadequate response to multiple lines of ...
Elena Ippoliti +5 more
wiley +1 more source
Molecularly targeted therapies for asthma: current development, challenges and potential clinical translation [PDF]
, 2016 Extensive research into the therapeutics of asthma has yielded numerous effective interventions over the past few decades. However, adverse effects and ineffectiveness of most of these medications especially in the management of steroid resistant severe ...
Lim, Jonathan Chee Woei +3 more
core +1 more source
Reduction of Rescue Treatment With Dupilumab for Chronic Rhinosinusitis With Nasal Polyps in Japan
The Laryngoscope, EarlyView.This observational study examined the impact of add‐on dupilumab treatment on the use of rescue therapy in Japanese individuals with chronic rhinosinusitis with nasal polyps (CRSwNPs) using data from a large hospital‐based administrative claims database.
Mamoru Yoshikawa +5 more
wiley +1 more source
Sinonasal Intervention Reduces the Need for Pressure Equalization Tube Placement in Atopic Adults
The Laryngoscope, EarlyView.Surgical and medical management of atopic sinonasal diseases decreases the risk of middle ear disease and the subsequent need for pressure equalization tubes. ABSTRACT Objectives To determine the impact of management of upper airway atopic disease on middle ear and eustachian tube function in adults.
Lawrance Lee +3 more
wiley +1 more source
Omalizumab as alternative to chronic use of oral corticosteroids in severe asthma
, 2019 Systemic/oral corticosteroids (OCS) have been used for decades in the management of acute asthma exacerbations and chronically in patients with uncontrolled severe asthma.
Bousquet, Jean +6 more
core +1 more source