Results 81 to 90 of about 14,376 (241)
Advanced Science, EarlyView.A Stringent dUPlex‐activated Error Robust (SUPER) DNAzyme system enables real‐time imaging of alternative mRNA splicing (e.g., Bcl‐xL/Bcl‐xS) in living cells via target‐triggered split‐DNAzyme reassembly and dual‐color fluorescence. It also achieves mRNA‐selective knockdown through DNAzyme‐based gene regulation, serving as a versatile tool for splicing
Mengru Lin +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.A membrane‐penetrating molecular device composed of triplex containing cholesterol‐modified acyclic L‐threoninol nucleic acid (L‐aTNA) was achieved. This device is applied to a photo‐triggered signal transduction system functioning on giant unilamellar vesicles. Abstract Membrane‐penetrating molecular devices are valuable biological tools.
Kaifu Liu +2 more
wiley +2 more sources
The Jardin d’Hiver in Paris, a Structural Glass Case Study
Challenging Glass Conference Proceedings, 2022 The 30 Avenue Montaigne in Paris, historical headquarters of Christian Dior on the Avenue Montaigne in Paris is currently undergoing a major refurbishment to be finished by early 2022.
Jorge Hidalgo +3 more
doaj
Advanced Science, EarlyView.We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li +10 more
wiley +1 more source
Farfalle: parallel permutation-based cryptography
IACR Transactions on Symmetric Cryptology, 2017 In this paper, we introduce Farfalle, a new permutation-based construction for building a pseudorandom function (PRF). The PRF takes as input a key and a sequence of arbitrary-length data strings, and returns an arbitrary-length output.
Guido Bertoni +5 more
doaj +1 more source
Advanced Science, EarlyView.Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu +8 more
wiley +1 more source
Angewandte Chemie, EarlyView.Here, we transform this otherwise destructive enzymatic activity into a powerful diagnostic advantage through an RNase I–assisted rolling circle amplification (RI‐RCA) strategy. By integrating controlled RNase I–mediated RNA digestion with circular DNA templates, this approach enables direct and highly sensitive detection of target RNA sequences. Using
Amal Mathai +5 more
wiley +2 more sources
Advanced Science, EarlyView.Photonic time crystals (PTCs) are systems in which electromagnetic parameters are modulated periodically in time, producing momentum bandgaps via temporal scattering rather than spatial Bragg processes. This review examines the theoretical frameworks, modeling, and computational tools for time‐varying media, and summarizes experimental demonstrations ...
Ranjan Kumar Patel +3 more
wiley +1 more source
Alternative Views of Authenticity
Ochrona Dziedzictwa KulturowegoPark Hill is the largest listed building in Europe. Opened in 1961, its design is an innovation on Le Corbusier’s Unité d’Habitation, with horizontal ‘streets in the sky’ at every third level, with duplex apartments extending above and below each access ...
Nigel Walter
doaj +1 more source
Advanced Science, EarlyView.By engineering ultrafine β‐subgrains and nanoscale α‐precipitates in titanium alloys, the unique architecture achieves an unprecedented ultra‐high strength of 2 GPa while maintaining a notable uniform elongation of 6%, a combination that is both rare and highly promising for structural applications of titanium alloys.
Dingxuan Zhao +10 more
wiley +1 more source