Results 31 to 40 of about 169,052 (260)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Validation of chemoresistance phenotypes in pleural mesothelioma across 2D, 3D, and in vivo models
Scientific ReportsPleural mesothelioma (PM) is a highly aggressive cancer with limited treatment efficacy and poor prognosis. Conventional two-dimensional (2D) culture models fail to replicate the tumour microenvironment (TME), limiting their translational relevance. Here,
Huaikai Shi +14 more
doaj +1 more source
Comparison of air distribution systems in ice rink arena ventilation
Mokslas: Lietuvos Ateitis, 2013 The paper presents the requirements and functions of ventilation in ice rink arenas and discusses difficulties and problems of ventilation in such objects.
Agnieszka Stobiecka +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Surveillance of Non-Malignant Asbestos-Related Diseases in an Exposed Population: A Scoping Review
Annals of Global HealthBackground: Asbestos remains a significant global public health issue, with approximately 255,000 deaths attributed to exposure each year, primarily through occupational contact.
Camilo de la Pava-Cortés +10 more
doaj +1 more source
Numerical Analysis of the Energy Consumption of Ventilation Processes in the School Swimming Pool
Energies, 2021 Ventilation of an indoor swimming pool is a very energy consuming process. This is a result of, among other things the required high value of the ventilation air volume flow rate, calculated on the basis of the moisture gains in the facility.
Piotr Ciuman, Jan Kaczmarczyk
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Tools of the trade: leveraging 3D in vitro models to advance silicosis research
Frontiers in PharmacologySilicosis is an occupational fibrotic lung disease representing a major public health crisis, and places a significant burden on patients and healthcare systems.
Ellen Donohoe +15 more
doaj +1 more source
Assessment of solar radiation distribution in indoor spaces for local thermal comfort evaluation [PDF]
E3S Web of ConferencesShortwave solar radiation significantly influences local thermal comfort in indoor environments, particularly in spaces with large glazed areas. Although building performance simulation tools such as EnergyPlus accurately predict solar gains at the room ...
Grygierek Krzysztof +3 more
doaj +1 more source
Particle and Fibre Toxicology, 2022 Background Coal dust particles (CDP), an inevitable by-product of coal mining for the environment, mainly causes coal workers’ pneumoconiosis (CWP).
Min Mu +13 more
doaj +1 more source