Results 51 to 60 of about 1,028,846 (258)
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Orbital-motion-limited theory of dust charging and plasma response
, 2014 The foundational theory for dusty plasmas is the dust charging theory that provides the dust potential and charge arising from the dust interaction with a plasma.
Delzanno, Gian Luca, Tang, Xian-Zhu
core +1 more source
Dusty Nuclear Disks and Filaments in Early Type Galaxies [PDF]
, 2001 We examine the dust properties of a nearby distance-limited sample of early type galaxies using the WFPC2 of the Hubble Space Telescope. Dust is detected in 29 out of 67 galaxies (43%), including 12 with small nuclear dusty disks. In a separate sample of
A. Rest +20 more
core +2 more sources
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
A correlation between the IRAS infrared cirrus at 60 or 100 microns and neutral atomic hydrogen in the outer galaxy [PDF]
A linear correlation was found between the infrared cirrus at 100 or 60 microns and neutral atomic hydrogen near the galactic plane. Infrared Astronomy Satellite (IRAS) Sky Brightness images were compared to the 0.5 deg resolution Weaver-Williams HI ...
hermal dust emission., Terebey, Susan
core +1 more source
How Do Martian Dust Devils Vary Throughout the Sol? [PDF]
, 2016 Dust devils are vortices of air made visible by entrained dust particles. Dust devils have been observed on Earth and captured in many Mars lander and orbiter images. Martian dust devils may be important to the global climate and are parameterised within
Balme, Matthew +3 more
core
, 2011 We have developed a numerical galactic chemical evolution model. The model is constructed such that the effect of a wide range of parameters can be investigated.
A. C. Andersen +93 more
core +2 more sources
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria
FEBS Open Bio, EarlyView.The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao +4 more
wiley +1 more source