Results 161 to 170 of about 1,574,380 (286)

A Dual‐Functional Nanoplatform Targeting the dsDNA–cGAS Axis to Mitigate Disc Degeneration and Aberrant Innervation

open access: yesAdvanced Science, EarlyView.
RU@PEI‐ZIF integrates dsDNA scavenging with local cGAS inhibition to suppress the dsDNA–cGAS–STING/Netrin‐1 axis in intervertebral disc degeneration. By attenuating nucleus pulposus cell senescence, inflammatory and matrix‐catabolic responses, and pathological sensory innervation, this dual‐functional nanoplatform preserves disc integrity and reduces ...
Zhaojun He   +12 more
wiley   +1 more source

A gas-enshrouded and gas-reddened black hole at cosmic dawn. [PDF]

open access: yesNature
Naidu RP   +53 more
europepmc   +1 more source

Porcupine‐Quill‐Inspired Shape‐Morphing Biointerfaces Disassemble Biofilms

open access: yesAdvanced Science, EarlyView.
A porcupine‐spine‐inspired dynamic offensive bio‐interface is developed for active biofilm disassembly. By coupling electrically driven nano‐dagger penetration with light‐triggered ROS generation, the surface overcomes the passive limitations of conventional mechano‐bactericidal topographies, achieving near‐complete biofilm eradication, strong ...
Feng Qian   +10 more
wiley   +1 more source

Red novae, their progenitors, and remnants. [PDF]

open access: yesAstron Astrophys Rev
Kamiński T, Blagorodnova N.
europepmc   +1 more source

Controlling Epitaxial Zn Growth via Guided Laser Patterning toward High‐Performance 6Ah Aqueous Zn||I2 Batteries

open access: yesAdvanced Science, EarlyView.
A scalable laser‐assisted surface patterning method regulates zinc ion flux and promotes lateral epitaxial growth for stable aqueous batteries. Periodic micro‐holes effectively minimize interfacial resistance and reconstruct the zinc texture to favor the compact (002) basal plane. This structured anode suppresses both dendrite propagation and parasitic
Suyeon Kim   +10 more
wiley   +1 more source

Magnetogravitationally regulated streamer accretion onto a class 0 protostellar system. [PDF]

open access: yesSci Adv
Huang B   +19 more
europepmc   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

open access: yesAdvanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun   +12 more
wiley   +1 more source

JWST interferometric imaging reveals the dusty torus obscuring the supermassive black hole of Circinus galaxy. [PDF]

open access: yesNat Commun
Lopez-Rodriguez E   +8 more
europepmc   +1 more source

Decoupling Stable Cyclic Deformation From Defect Accumulation in Metals

open access: yesAdvanced Science, EarlyView.
Introducing amorphous nanoparticles into a metal matrix enables a cyclic deformation regime where strain hardening and defect accumulation are decoupled. These nanoparticles act as dislocation sinks and undergo reversible shear transformations, sustaining microstructural stability over millions of cycles.
Chenjun Ye   +9 more
wiley   +1 more source

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