Results 91 to 100 of about 2,096,377 (330)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
EXTENDED CREDIT OPPORTUNITIES FOR BUSINESS ENTITIES IN CONDITIONS OF IMPORT SUBSTITUTION
Финансы: теория и практика, 2017 The article assesses the opportunities for developing credit relations between economic entities in conditions of import substitution industrial policy. The author concludes that there is a need to attract new lenders because of the increased demand for ...
N. P. Simaeva
doaj +1 more source
Middle Theory, Inner Freedom, and Moral Health [PDF]
, 2007 In her influential book, The Practice of Moral Judgment, Barbara Herman argues that Kantian ethics requires a “middle theory” applying formal rational constraints on willing to the particular circumstances and nature of human existence.
Wilson, Donald
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
An Incongruent Amalgamation: John Stuart Mill\u27s Utilitarianism on Naturalism [PDF]
, 2015 John Stuart Mill\u27s utilitarian principle of the greatest happiness for the greatest number, often surfaces in cultural debates in the contemporary West over the extent and foundations of moral duties.
Robinson, Jeffrey M
core +1 more source
The future Scotland wants:Is it really all about sustainable economic growth? [PDF]
, 2015 This article analyses the legal and practical implications of the Scottish Government's overall stated objective of increasing sustainable economic growth and the further implications that arise now that the term is formalised in legislation. It draws on
Andrea Ross +3 more
core +3 more sources
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
TUGAS DAN FUNGSI BADAN PENANGGULANGAN BENCANA
Jurnal Magister Hukum Udayana, 2014 The main issue of this research is the enactment of Act No. 24of 2007 regarding Disaster Management, there is a body of disaster management (BNBP and BPBDs) national and regional scale is still in charge, and on the other hand there is an Act No.23 /Prp ...
Ni Ketut Sri Utari
doaj +1 more source