Results 91 to 100 of about 7,254 (221)

DxR Clinician - Congenital Defect Case (Out of Print)

open access: yesMedEdPORTAL, 2006
Abstract Health care professionals face the difficult task of determining the clinical reasoning skills of individual students. While observing and mentoring students during preclinical patient encounters and clinical clerkships can provide considerable insight into the clinical reasoning procedure, they do not provide any means of quantifying specific
openaire   +2 more sources

Fosmidomycin for the Treatment of Canine Otitis Externa: A Randomised, Double‐Blinded, Controlled ‘Split Body’ Clinical Trial

open access: yesVeterinary Dermatology, Volume 37, Issue 3, Page 427-436, June 2026.
ABSTRACT Background Targeted antimicrobial therapy for canine otitis externa (OE) represents an opportunity for antimicrobial stewardship. Fosmidomycin selectively inhibits the non‐mevalonate pathway for isoprenoid biosynthesis utilised by canine‐adapted, and not human‐adapted, staphylococci.
Lindsey E. Citron   +6 more
wiley   +1 more source

Time-dependent apoptosis following DXR insult is follicle type-dependent.

open access: yes, 2012
A. Graph plots mean apoptotic index for secondary, early antral, and late antral follicles over a 48-hour time period post-DXR injection. B. Graph plots mean apoptotic index for primordial and primary follicles over a 48-hour time period post-DXR ...
Elon C. Roti Roti (148117)   +3 more
core   +1 more source

Nilotinib counteracts P-glycoprotein-mediated multidrug resistance and synergizes the antitumoral effect of doxorubicin in soft tissue sarcomas.

open access: yesPLoS ONE, 2012
The therapeutic effect of doxorubicin (DXR) in the treatment of soft tissue sarcomas (STS) is limited by its toxicity and the development of multidrug resistance (MDR), the latter mainly induced by high expression of efflux pumps (e.g., P-glycoprotein [P-
Victor Hugo Villar   +8 more
doaj   +1 more source

Investigation of Structural, Mechanical and Electrochemical Properties of Temperature‐Dependent Dual AlN/TiAlN Coating Synthesized by CVD Process

open access: yesAdvanced Materials Interfaces, Volume 13, Issue 9, 5 May 2026.
This study investigates thermally CVD‐deposited AlN/TiAlN dual‐layer coatings over a Si substrate, focusing on the temperature‐dependent process‐structure relationship. Systematic characterization reveals that a dense AlN interlayer combined with an optimally deposited TiAlN top layer provides enhancement in mechanical strength, tribological stability,
Soham Das   +4 more
wiley   +1 more source

Targeted Delivery of GLUT1 Inhibitor via Macrophage Nanovesicles for Pulmonary Arterial Hypertension Therapy

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
Mac@WZB117 to target M1 macrophage glycolysis, remodel the immune microenvironment, and attenuate vascular remodelling in PAH. ABSTRACT Pulmonary arterial hypertension (PAH) is a lethal disease characterized by inflammation‐driven vascular remodelling, with a lack of precise intervention strategies targeting pro‐inflammatory M1 macrophages' glycolytic ...
Yanzi Guo   +3 more
wiley   +1 more source

Synergistically Enhanced Inhibitory Effects of Pullulan Nanoparticle-Mediated Co-Delivery of Lovastatin and Doxorubicin to Triple-Negative Breast Cancer Cells

open access: yesNanoscale Research Letters, 2019
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is prone to drug resistance and difficult to treat. In this study, we grafted water-soluble pullulan with lovastatin (LV) to develop a novel amphiphilic conjugate, pullulan ...
Di Wu   +11 more
doaj   +1 more source

Synergistic Engineering of Amorphous Cathode and Hybrid Electrolyte Toward Stable High‐Voltage Aqueous Zn‐Ion Batteries

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT The development of high‐voltage aqueous zinc‐ion batteries (AZIBs) is primarily hindered by the lack of suitable cathode materials and electrolytes that can work in broad voltage windows. Herein, we propose a synergistic strategy that concurrently addresses these challenges through the integration of an amorphous vanadium oxyphosphate/graphene
Xianyu Liu   +7 more
wiley   +1 more source

Association between cortical DXR-porosity and current distal radius fracture.

open access: yes, 2013
Association between cortical DXR-porosity and current distal radius fracture tested in unadjusted and adjusted logistic regression models.aAdjusted for age.bInflammatory or endocrine disease (fracture group vs.
Glenn Haugeberg (38721)   +3 more
core   +1 more source

Bort pretreatment prevents DXR-induced dsDNA breaks in ovarian cells.

open access: yes, 2014
Summary data quantify dsDNA damage as the comet moment utilizing the comet assay. Trend lines included for visualization. Panels summarize DNA damage in granulosa cells (A.) and stromal cells (B.) as time post-DXR injection plotted against comet moment ...
Elon C. Roti Roti (148117)   +4 more
core   +1 more source

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