Results 71 to 80 of about 5,908 (179)

Chemotherapy-induced late transgenerational effects in mice. [PDF]

open access: yesPLoS ONE, 2011
To our knowledge, there is no report on long-term reproductive and developmental side effects in the offspring of mothers treated with a widely used chemotherapeutic drug such as doxorubicin (DXR), and neither is there information on transmission of any ...
Loro L Kujjo   +8 more
doaj   +1 more source

Targeting Dxr/IspC to develop drugs against malaria and tuberculosis

open access: yesThe FASEB Journal, 2019
The methylerythritol phosphate pathway (the MEP pathway) of isoprenoid biosynthesis is essential for the survival of many pathogenic organisms, including Plasmodium falciparum and Mycobacterium tuberculosis , causative agents of malaria and tuberculosis,
Misgina Belachew Girma   +3 more
openaire   +1 more source

Thickness‐Dependent Plasma Activation in Binder‐Free Multilayer Ni–Co–O Anodes for Alkaline Oxygen Evolution

open access: yesAdvanced Energy and Sustainability Research, Volume 7, Issue 7, July 2026.
Depth‐limited nitrogen plasma activation in binder‐free multilayer Ni–Co–O anodes enables thickness‐dependent surface modification. Plasma treatment induces enrichment of Co at the surface, increases nanoscale roughness and pore density, improves wettability, and strengthens interfacial cohesion.
Mohit Chatwani   +15 more
wiley   +1 more source

Multi‐Induction Strategies in Crops: Mechanisms, Synergistic Effects, and Sustainable Applications for Enhanced Secondary Metabolite Production

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
This review analyzes single/combined abiotic (light, water, nutrients, hormones) and biotic (microbes, yeast) elicitors regulating signaling, gene expression, and metabolism to boost plant secondary metabolites. It highlights synergistic multielicitor strategies for crop quality and functional foods, while critically addressing current limitations and ...
Yifei Sun   +6 more
wiley   +1 more source

Strain‐Specific Biotransformation of Grape Marc by Lactic Acid Bacteria: Genomic Validation and Gut Microbiota Modulation

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Grape marc (GM) is a polyphenol‐rich winery byproduct that remains underutilized due to its complex fiber matrix, which limits the bioaccessibility of bound phenolics. While lactic acid fermentation (LAF) can enhance the release of these compounds, the strain‐specific metabolic fate of GM phenolics during digestion and colonic fermentation ...
Ziyao Liu   +4 more
wiley   +1 more source

Fast Solvation Dynamics Enabled by High Entropy Electrolyte Design for Low Temperature Lithium‐Ion Batteries

open access: yesSmall Structures, Volume 7, Issue 7, July 2026.
A propylene carbonate‐based high‐entropy electrolyte weakens Li+–PC coordination, diversifies the Li+ solvation environment, and accelerates solvation‐shell exchange. The nitrile/carbonate co‐solvent design suppresses PC co‐intercalation, promotes stable interphase formation on graphite, and enables fast ion transport as well as stable graphite||NMC622
Sangyun Yeo   +5 more
wiley   +1 more source

Hierarchical MXene‐Derived NTP/C Nanohybrids for Cryogenic Sodium‐Ion Batteries

open access: yesAdvanced Functional Materials, Volume 36, Issue 52, 29 June 2026.
A hierarchical MXene‐derived NaTi2(PO4)3/C nanohybrid enables efficient sodium‐ion storage down to −40°C by integrating fast ion–electron transport pathways with an ether‐based electrolyte. The system promotes dominant pseudocapacitive behavior and forms a robust inorganic‐rich SEI, collectively mitigating kinetic and interfacial limitations, thereby ...
M. Sai Bhargava Reddy   +5 more
wiley   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

open access: yesAdvanced Materials, Volume 38, Issue 31, 2 June 2026.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen   +16 more
wiley   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

open access: yesAdvanced Science, Volume 13, Issue 35, 24 June 2026.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao   +11 more
wiley   +1 more source

Reduction of doxorubicin-induced genotoxicity by Handroanthus impetiginosus in mouse bone marrow revealed by micronucleus assay

open access: yesBrazilian Journal of Biology, 2017
Handroanthus impetiginosus has long been used in traditional medicine and various studies have determined the presence of bioactive chemical compounds and potential phytotherapeutics.
M. F. G. Boriollo   +8 more
doaj   +1 more source

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