Results 61 to 70 of about 7,254 (221)

Dalbergioidin Ameliorates Doxorubicin-Induced Renal Fibrosis by Suppressing the TGF-β Signal Pathway

open access: yesMediators of Inflammation, 2016
We investigated the effect of Dalbergioidin (DAL), a well-known natural product extracted from Uraria crinita, on doxorubicin- (DXR-) induced renal fibrosis in mice.
Xianguo Ren   +11 more
doaj   +1 more source

A Comparison of Doxorubicin-Resistant Colon Cancer LoVo and Leukemia HL60 Cells: Common Features, Different Underlying Mechanisms

open access: yesCurrent Issues in Molecular Biology, 2021
Chemoresistance causes cancer relapse and metastasis, thus remaining the major obstacle to cancer therapy. While some light has been shed on the underlying mechanisms, it is clear that chemoresistance is a multifaceted problem strictly interconnected ...
Laura Locatelli   +7 more
doaj   +1 more source

Vector-Field dynamic X-ray (VF-DXR) using Optical Flow Method

open access: yesThe British Journal of Radiology, 2021
Objectives: To explore the feasibility of Vector-Field DXR (VF-DXR) using optical flow method (OFM). Methods: Five healthy volunteers and five COPD patients were studied.
Takuya Hino   +9 more
openaire   +2 more sources

Multi‐Induction Strategies in Crops: Mechanisms, Synergistic Effects, and Sustainable Applications for Enhanced Secondary Metabolite Production

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
This review analyzes single/combined abiotic (light, water, nutrients, hormones) and biotic (microbes, yeast) elicitors regulating signaling, gene expression, and metabolism to boost plant secondary metabolites. It highlights synergistic multielicitor strategies for crop quality and functional foods, while critically addressing current limitations and ...
Yifei Sun   +6 more
wiley   +1 more source

Dexra pretreatment prevents DXR-induced infertility of mice over time.

open access: yes, 2015
An “infertility index” was calculated as the percentage of surviving mice that failed to achieve pregnancy and deliver at 30-day intervals through 8 months of age.
Elon C. Roti Roti (148117)   +5 more
core   +1 more source

Strain‐Specific Biotransformation of Grape Marc by Lactic Acid Bacteria: Genomic Validation and Gut Microbiota Modulation

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Grape marc (GM) is a polyphenol‐rich winery byproduct that remains underutilized due to its complex fiber matrix, which limits the bioaccessibility of bound phenolics. While lactic acid fermentation (LAF) can enhance the release of these compounds, the strain‐specific metabolic fate of GM phenolics during digestion and colonic fermentation ...
Ziyao Liu   +4 more
wiley   +1 more source

Dexra pretreatment prevents DXR-induced decrease in pup weight.

open access: yes, 2015
Weight measured in grams (g) on PND1 and represented as mean weight for each treatment. Error bars indicate the SE of the mean pup weight. Letters above data points represent groups that significantly differ from one another, one-way ANOVA with ...
Elon C. Roti Roti (148117)   +5 more
core   +1 more source

Chromosome damage induced by DNA topoisomerase II inhibitors combined with g-radiation in vitro

open access: yesGenetics and Molecular Biology, 1998
Combined radiation and antineoplastic drug treatment have important applications in cancer therapy. In the present work, an evaluation was made of two known topoisomerase II inhibitors, doxorubicin (DXR) and mitoxantrone (MXN), with g-radiation.
Maria Cristina P. Araújo   +4 more
doaj   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

open access: yesAdvanced Materials, Volume 38, Issue 31, 2 June 2026.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen   +16 more
wiley   +1 more source

Bort pretreatment increases pup number per litter and ovarian weight following DXR.

open access: yes, 2014
Number of pups birthed in each litter were counted and weighed for each treatment group. A. Plot depicts the mean number of pups per litter (± SE) for each litter number for each dam treatment group.
Elon C. Roti Roti (148117)   +4 more
core   +1 more source

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