Results 61 to 70 of about 6,069 (180)
Expanding the Genetic Toolkit of Pichia kudriavzevii E1 for Enhanced Mycoprotein Production
Microbial Biotechnology, Volume 19, Issue 9, September 2026.A library of endogenous promoters with a 455‐fold activity range was developed using an established episomal expression vector in the Pichia kudriavzevii E1 strain. The promoter library was used to regulate genes associated with nitrogen assimilation and pyruvate metabolism to enhance mycoprotein production.
Yupeng Wang +7 more
wiley +1 more source
Out of the blue: family‐wide loss of anthocyanin biosynthesis in Cucurbitaceae
The Plant Journal, Volume 127, Issue 6, September 2026.Significance Statement Anthocyanins are nearly universal plant pigments, making their evolutionary loss unexpected. Phylogenomics across Cucurbitaceae reveals the consistent absence of key structural and regulatory genes in the anthocyanin and proanthocyanidin pathways, indicating a family‐wide pathway loss. We propose Cucurbitaceae as a ‘natural knock‐
Nancy Choudhary +2 more
wiley +1 more source
Targeting Dxr/IspC to develop drugs against malaria and tuberculosis
The FASEB Journal, 2019 The methylerythritol phosphate pathway (the MEP pathway) of isoprenoid biosynthesis is essential for the survival of many pathogenic organisms, including Plasmodium falciparum and Mycobacterium tuberculosis , causative agents of malaria and tuberculosis,
Misgina Belachew Girma +3 more
openaire +1 more source
Journal of Interactive Media in Education, 1998 : Clinical reasoning is essentially a problem-solving process, in which medical students must learn to gather and interpret data, generate hypotheses and make decisions.
Deborah A. Bryce +3 more
doaj +1 more source
Scientific Reports, 2022 Up to now, there is only limited information available on a possible relationship between clinical characteristics and the mineralization of metacarpal bones and finger joint space distance (JSD) in patients with psoriatic arthritis (PsA).
Alexander Pfeil +10 more
doaj +1 more source
Advanced Engineering Materials, Volume 28, Issue 16, 19 August 2026.X‐ray computed tomography reveals how process‐induced defects evolve from green to sintered states in Fused Filament Fabrication (FFF)‐manufactured 17‐4PH stainless steel. Internal porosity, weakest cross‐sections, and fracture locations show strong correlation with tensile performance, demonstrating the potential of computed tomography (CT)‐based ...
György Ledniczky +3 more
wiley +1 more source
Genetics and Molecular Biology, 2007 In this study two different crosses involving the wing cell markers mwh and flr³ (standard (ST) cross and high bioactivation (HB) cross, the latter being characterized by a high constitutive level of cytochrome P450 which leads to an increased ...
Edson José Fragiorge +2 more
doaj +1 more source
PLoS ONE, 2012 The therapeutic effect of doxorubicin (DXR) in the treatment of soft tissue sarcomas (STS) is limited by its toxicity and the development of multidrug resistance (MDR), the latter mainly induced by high expression of efflux pumps (e.g., P-glycoprotein [P-
Victor Hugo Villar +8 more
doaj +1 more source
Nano Carbon‐mesh with Excellent Bonding Performance via Hydro‐cage De‐shielding Strategy
Advanced Science, Volume 13, Issue 44, 7 August 2026.A hydro‐cage de‐shielding strategy transforms cellulose‐based films into a dragonfly‐wing‐like nano carbon‐mesh (NCM) adhesive through instantaneous carbonization‐polymerization. The resulting NCM‐plywood achieves exceptional wet shear strength (1.24 MPa at 63°C), exceeding Class II plywood standards, and retains 0.73 MPa after boiling‐water cycles ...
Weijia Yang +14 more
wiley +1 more source
eFood, Volume 7, Issue 4, August 2026.This study establishes that fruit color divergence in Yanjiao pepper cultivars arises from hierarchical regulation of carotenoid metabolism, driven by yellow‐blue chromaticity variation and cultivar‐specific metabolic strategies. These findings provide a mechanistic framework for breeding peppers with enhanced color stability and nutraceutical value ...
Qi Chen +5 more
wiley +1 more source