Results 41 to 50 of about 7,254 (221)
Immunolocalization of DXR-GFP in vesicles.
, 2016 Cross-sections of cotyledons from transgenic plants expressing DXR-GFP (H line) and untransformed wild type controls (C) were used for immunogold labelling with anti-DXR serum and observed at the transmission electron microscopy (TEM) level.
Manuel Rodriguez-Concepcion (310794) +6 more
core +1 more source
Stem Cells International, 2020 The precise mechanism about drug resistance of cancer stem cells (CSCs) has not yet been completely understood. Based on the expression of CD44 and CD133, two well-recognized cell surface markers for CSC identification, we tried to separate HCT8 ...
Shinji Goto +2 more
doaj +1 more source
MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria [PDF]
Journal of Medicinal Chemistry, 2018 Severe malaria due to Plasmodium falciparum remains a significant global health threat. DXR, the second enzyme in the MEP pathway, plays an important role to synthesize building blocks for isoprenoids. This enzyme is a promising drug target for malaria due to its essentiality as well as its absence in humans.
Xu Wang +16 more
openaire +2 more sources
Nano Carbon‐mesh with Excellent Bonding Performance via Hydro‐cage De‐shielding Strategy
Advanced Science, EarlyView.A hydro‐cage de‐shielding strategy transforms cellulose‐based films into a dragonfly‐wing‐like nano carbon‐mesh (NCM) adhesive through instantaneous carbonization‐polymerization. The resulting NCM‐plywood achieves exceptional wet shear strength (1.24 MPa at 63°C), exceeding Class II plywood standards, and retains 0.73 MPa after boiling‐water cycles ...
Weijia Yang +14 more
wiley +1 more source
DXR accumulation differed according to follicle class.
, 2012 A. Graph depicts mean total DXR fluorescence intensity for each follicle class (primordial, primary, secondary, early antral, late antral) plotted over time.
Elon C. Roti Roti (148117) +3 more
core +1 more source
Porcine kidney xenotransplantation: From primate models to clinical reality
Animal Models and Experimental Medicine, EarlyView.In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo +3 more
wiley +1 more source
Journal of Saudi Chemical Society, 2016 The present study was conducted with the aim of evaluating the protective effects of Bombyx mori, quercetin and benazepril on doxorubicin (DXR) induced cardiotoxicity and nephrotoxicity in rats. B.
Abdul S. Nazmi +5 more
doaj +1 more source
Cardiovascular Organoids With Adjustable Endothelial Composition via SOX17‐Engineered hPSCs
Biotechnology and Bioengineering, EarlyView.ABSTRACT Organoids are considered a novel modeling platform for studying human biology and advancing health research. With the ability to demonstrate complex 3D structure and multicellular interactions, organoids have advanced studies in all major organs as a reliable model.
Po‐Yu Liang +4 more
wiley +1 more source
DXR accumulation in the ovary and follicle was time-dependent.
, 2012 A. Graph of total DXR fluorescence intensity in the ovary as a function of time reveals DXR accumulation in the ovary follows an exponential fit, with signal rapidly rising through 4 hours post-injection, followed by plateau (n = 4). B.
Elon C. Roti Roti (148117) +3 more
core +1 more source
BMC Cancer, 2017 Background Doxorubicin (DXR) hydrochloride (HCl) liposome injection is an important part of the treatment armamentarium for a number of cancers. With growing needs for affordable and effective anticancer treatments, the development of generics is ...
Vinod Burade +5 more
doaj +1 more source