Results 1 to 10 of about 4,695 (193)

Dydrogesterone and Letrozole Combination for the Treatment of Endometriosis: A Mechanism-Based Therapeutic Approach [PDF]

Obstetrics and Gynecology International
Endometriosis is a complex, estrogen-dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology.
Santosh Kumar Rai, Rakesh Kumar, Mohd Imran Khan, Anil Kumar   +3 more
doaj   +2 more sources

Effectiveness of oral dydrogesterone compared to placebo in reducing the risk of preterm birth: a systematic review and meta-analysis [PDF]

BMC Pregnancy and Childbirth
Background Preterm birth remains a major contributor to neonatal morbidity and mortality worldwide. Oral dydrogesterone is used in some clinical settings for preterm birth prevention, despite uncertainty regarding its effectiveness.
Sohieb Hedawy, Shahed Aldalahmeh, Eman E. Labeeb, Abdelrahman A. Khattab, Esraa Khalid, Ahmed Hassan, Ahmed Menshawy   +6 more
doaj   +2 more sources

Age-stratified analysis of euploidy rates in Progestin-Primed Ovarian Stimulation (PPOS) utilizing micronized progesterone or dydrogesterone versus GnRH analogues [PDF]

Journal of Ovarian Research
Purposes This study aims to analyze the euploidy rates of PPOS utilizing micronized progesterone and dydrogesterone in comparison to conventional controlled ovarian stimulation (COS) protocols in pre-implantation genetic testing for aneuploidy (PGT-A ...
Rang Liu, Xinyi Pan, Yutong Wang, Rui Xiang, Shaohong Zhuang, Xiaoting Diao, Cong Fang, Xiaoyan Liang, Haitao Zeng   +8 more
doaj   +2 more sources

No improvement in pregnancy and perinatal outcomes with combined luteal support in modified natural cycle frozen embryo transfer [PDF]

Frontiers in Endocrinology
ObjectiveWe investigated whether the addition of a luteal phase support drug benefits pregnancy and perinatal outcomes in modified natural-cycle frozen-thawed embryo transfer (mNC-FET) for women up to the age of 35 years.MethodsWe analyzed the clinical ...
Wen Zhang, Sheling Wu, Bingnan Ren, Ruolin Jia, Wenjuan Zhang, Bijun Wang, Xiaofang Du, Yichun Guan   +7 more
doaj   +2 more sources

Effectiveness of innovator dydrogesterone versus generic dydrogesterone in early pregnancy: a real-world analysis [PDF]

International Journal of Reproduction, Contraception, Obstetrics and Gynecology
Background: Miscarriage is the most common complication of early pregnancy. Dydrogesterone, a retro-steroid with high oral bioavailability and receptor selectivity, is widely prescribed to support and maintain pregnancy via its novel immunomodulation mechanism.  There is a lack of comparative data on the miscarriage rate for pregnant females prescribed
Sunita Jamwal, Sandeep Gudibanda, Snehal Shah, Supriya Kaloo, Malvika Sharma, Vaibhav Miglani, Jayanthy Govindaraj, Garima Verma   +7 more
openaire   +3 more sources

Systematic use of long-acting intramuscular progesterone in addition to oral dydrogesterone as luteal phase support for single fresh blastocyst transfer: A pilot study

Frontiers in Endocrinology, 2022
ObjectiveThe need of luteal support after FET is no longer to be proven. Different routes of progesterone administration are available with interindividual differences in metabolization and serum progesterone levels, the latter being highly correlated ...
Virginie Simon, Virginie Simon, Geoffroy Robin, Geoffroy Robin, Laura Keller, Camille Ternynck, Camille Ternynck, Sophie Jonard, Sophie Jonard, Camille Robin, Christine Decanter, Pauline Plouvier   +11 more
doaj   +1 more source

Evaluation of allylestrenol for clinical pregnancies in patients treated with assisted reproductive techniques: a retrospective, propensity score matched, observational study

BMC Pregnancy and Childbirth, 2023
Background Allylestrenol is an oral progestogen being increasingly used for luteal phase support in assisted reproductive techniques. However, evidence of the clinical efficacy of allylestrenol in luteal phase support is lacking.
Yuexin Yu, Tingting Yu, Weiping Ding, Yinling Xiu, Mengsi Zhao, Kaixuan Sun, Qian Zhang, Xiaohang Xu   +7 more
doaj   +1 more source

Efficacy and safety of Gushen Antai Pills combined with dydrogesterone in the treatment of threatened miscarriage: a systematic review and meta-analysis

Frontiers in Pharmacology, 2023
Background: Despite some progress has been made in the pathogenesis and treatment of threatened miscarriage (TM), conventional treatment remains suboptimal.
Kai Chen, Xiaoxia Liu, Xianhua Meng, Hui Li, Chenchen Yang, Xiaohong Wang   +5 more
doaj   +1 more source

Progestagens in high-risk pregnancy. What we know today

Репродуктивная эндокринология, 2023
Miscarriage remains an important global problem: 23 million miscarriages are registered annually in the world, i.e. 44 pregnancy losses every minute, and the total risk of miscarriage is 15.3% of all pregnancies.
N.Y. Pedachenko, N.P. Goncharuk, E.F. Chaikivska, T.F. Tatarchuk, T.M. Tutchenko   +4 more
doaj   +1 more source

Endometriosis: impact on fertility and pregnancy outcomes

Гинекология, 2021
Aim. To investigate the modern condition of the problem of infertility and obstetric complications in endometriosis and the main management aspects of women with endometriosis in pregnancy planning. Materials and methods.
Rushania I. Gabidullina, Ekaterina A. Koshelnikova, Tatiana N. Shigabutdinova, Evgenii A. Melnikov, Gulfiria N. Kalimullina, Angelina I. Kuptsova   +5 more
doaj   +1 more source