Results 121 to 130 of about 32,127,622 (336)
Development of an Autonomous Underwater Helicopter with High Maneuverability
Applied Sciences, 2019 Autonomous Underwater Vehicles (AUVs) are the mainstream equipment for underwater scientific research and engineering. However, it remains a great challenge for AUVs to carry out near-seabed operations because of their poor maneuverability. In this paper,
Zhikun Wang +3 more
doaj +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
AxiomsIn this paper, we investigate a nonlinear coupled integro-differential system involving generalized Hilfer fractional derivative operators ((k,ψ)-Hilfer type) of different orders and equipped with non-local multi-point ordinary and fractional integral ...
Chayapat Sudprasert +4 more
doaj +1 more source
Dynamic Assessment and Change Analysis of Ecosystem Service Value Based on Physical Assessment Method in Cili County, China [PDF]
, 2023 Xinchuang Wang +4 more
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Dynamic Behavior of Lighting GFRP Pole Under Impact Loading
BuildingsVehicle collisions with street lighting poles generate extremely high impact forces, often resulting in serious injuries or fatalities. Therefore, enhancing the structural resilience of pole bases is a critical engineering objective.
Mahmoud T. Nawar +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source