Results 101 to 110 of about 2,721,644 (298)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Investigating the role of dynamic assessment on speaking accuracy and fluency of pre-intermediate EFL learners

Cogent Education, 2020
The current study set out to investigate the effect of dynamic assessment (DA) on the speaking accuracy and fluency of pre-intermediate English as a foreign language (EFL) learners. In contrast to static assessment, DA is conceptualized as an interactive
Maryam Safdari, Jalil Fathi
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Evaluation model of construction quality data uncertainty: a study based on industry park project

Journal of Civil Engineering and Management
This study proposes an evaluation and adjustment model for construction quality data uncertainty based on the research project of the Sichuan Provincial Building Industry Park.
Changhao Fu, Weijie Xu, Junchi Liu, Qingzi Ge, Hang Bai, Tong Guo, Tao Wang   +6 more
doaj   +1 more source

Structural optimisation problem in support to building retrofitting decision [PDF]

, 2005
Various analysis methods, either linear elastic or non-linear, static or dynamic, are available for the performance analysis of existing buildings. Despite its advantages, it must be admitted that non-linear time history analysis can frequently become ...
Costa, A., Pinto, A., Varum, H.
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

A terminal assessment of stages theory : introducing a dynamic states approach to entrepreneurship [PDF]

, 2009
Stages of Growth models were the most frequent theoretical approach to understanding entrepreneurial business growth from 1962 to 2006; they built on the growth imperative and developmental models of that time. An analysis of the universe of such models (
Afuah A., Aldrich H., Ancona D., Anderson P., Autio E., Axelrod R., Baron R.A., Bhidé A., Birch D., Birch D.L., Birley S., Chandler A.D., Christensen C.R., Churchill N.C., Dean J., Dhalla N.K., Dubin R., Eggers J.H., Epstein M.J., Gardner J.W., Gartner W., Greiner L., Greiner L., Gupta Y.P., Hanks S.H., Hawken P., Holland J., Kauffman S., Kaufman H., Kimberly J.R., Kuratko D.F., Leibenstein H., Lichtenstein B., Lippitt G.L., Marshall A., Meyer A., Nicholls–Nixon C., Normann R., Pennings J., Penrose E., Prigogine I., Reynolds P.D., Rhenman E., Rostow W.W., Sahlman W.A., Schaltegger S., Schoonhoven C.B., Schori T.R., Schrödinger E., Scott B.R., Scott R., Senge P., Small Business Administration, Starbuck W.H., Stevenson H., Thompson J., Timmons J.A., Toynbee A.J., Tushman M.L., Webster's   +59 more
core   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Dynamic assessment in English classrooms: Fostering learners’ reading comprehension and motivation

Cogent Psychology, 2020
An important goal of educational research is to find out which teaching practices are effective in promoting students’ learning. Given the importance of reading comprehension in English language teaching (ELT), the current quantitative classroom-based ...
Akram Kazemi, Mohammad Sadegh Bagheri, Ehsan Rassaei   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source