Results 81 to 90 of about 703,629 (254)

Dynamic assessment and analysis of comprehensive ability of clinical nurse based on hierarchical management

open access: yesHuli yanjiu, 2015
Objective:On the basis of nurses’ hierarchical management,to carry out dynamic assessment of clinical nurses’ comprehensive ability,so as to provide references for improving the comprehensive ability of nurses and rational use of nurses.Methods:On the ...
杨志兰, 甘红霞, 周建芳
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Dynamic Assessment as A Strategy to Enhance Deep Learning in Narrative Writing for Elementary School Students

open access: yesEducational Process: International Journal
Background/purpose. This study aims to analyze the application and impact of dynamic assessment as an enhancement of deep learning in writing narratives for elementary school students.
Suparti Suparti   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

EFL teachers’ recruitment and dynamic assessment in private language institutes of Iran [PDF]

open access: yesJournal of English Language Teaching and Learning, 2012
The critical role and effect of teacher assessment in ELT has been ratified by researchers among whom are Darling-Hammond (2000); Knox (2002); Bailey (2006); Davison & Cummins (2007); and Blum (2009).Taking this issue into account, this exploratory study
Ramin Akbari, Elham Yazdanmehr
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Towards a Dynamic Approach to Assessing Students’ Critical Thinking Skills in Higher Education

open access: yesTraduction et Langues, 2019
The present article probes the perceptions of first year English degree students towards their teachers’ assessment. University teachers’ literacy and attitudes towards dynamic assessment in EFL classes are also investigated.
Lydia Benmihoub, Yasmine Boukhedimi
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

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