Results 61 to 70 of about 797,481 (300)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

New technologies in psychological assessment: The example of computer-based collaborative problem solving assessment [PDF]

open access: yes, 2013
Computer-based assessment is a relatively new but exponentially growing field in psychological assessment. Its advantages are numerous – flexibility of application, the opportunity to use video and audio material, the construction of dynamic tasks,
Molnar, G.   +9 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

فاعليَّـة برنامـج تدريبيّ مقتـرح قائـم على التقييـم الدينامـي في تنمية العمليَّات المعرفيَّة لدى الطالبات ذوات صعوبات التعلمThe Effectiveness of a Proposed Training Program Based on Dynamic Assessment in Enhancing Cognitive Processes Among Female Students with Learning Disabilities [PDF]

open access: yesمجلة التربیة الخاصة والتأهیل
هدفت الدراسة الحالية إلى التعرُّف على فاعليَّة برنامج تدريبيّ مقترح قائم على التقييم الدينامي في تنمية العمليَّات المعرفيَّة لدى الطالبات ذوات صعوبات التعلم بالصف الثالث الابتدائيّ، والتعرُّف على دلالة الفروق الإحصائيَّة بين القياسين: القبليّ والبعدي ...
منال شعبان   +1 more
doaj   +1 more source

Performance monitoring of MPC based on dynamic principal component analysis

open access: yes, 2011
A unified framework based on the dynamic principal component analysis (PCA) is proposed for performance monitoring of constrained multi-variable model predictive control (MPC) systems.
Gong Quan Chen   +7 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Synthesizing transformative education with dynamic assessment in developing EFL learners’ productive skills

open access: yesCogent Arts & Humanities, 2020
This study was an initiative to investigate the extent to which synthesizing Transformative Education (TE) with Dynamic Assessment (DA) can contribute to developing EFL learners’ productive skills; speaking and writing.
Azadeh Zarbafian   +3 more
doaj   +1 more source

Developing a dynamic assessment instrument to assess reasoning skills about bacteria

open access: yesJurnal Penelitian dan Evaluasi Pendidikan, 2020
This study was aimed to develop instruments to assess reasoning skills in the form of dynamic assessment as a formative assessment to improve students’ reasoning skills about bacteria. The cake format and graduated prompting method was used in this study.
Mayasari Mahfudhotul Khasanah   +2 more
doaj   +1 more source

Modelling the vehicle in vehicle-infrastructure dynamic interaction studies

open access: yes, 2010
This paper presents the equations of motion for a general articulated road vehicle, with variable numbers of wheels for the tractor and trailer. The equations are applicable to vehicle-bridge dynamic interaction problems for two and three dimensional ...
O\u27Brien, Eugene J.   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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