Results 181 to 190 of about 1,307,758 (299)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

DYNAMIC GREEN CAPABILITIES

open access: yesIsagoge - Journal of Humanities and Social Sciences
This comprehensive review explores the evolution from dynamic capabilities to dynamic green capabilities (GDCs) in the context of sustainable business practices. It examines the theoretical foundations, drivers, and challenges in developing GDCs across various industries. The study highlights the critical role of GDCs in enabling firms to sense, seize,
openaire   +1 more source

Intercompartmental communication in senescence

open access: yesFEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz   +3 more
wiley   +1 more source

Board Dynamic Capability

open access: yes, 2014
The emerging contemporary approach to corporate governance field emphasizes a holistic perspective, i.e. organizational level of governing the corporation. Since the ongoing business reality assumes a complex, ever-changing corporate ecosystem that requires governance excellence, a permanent upgrading of governance practice is needed in order to ...
Tomšić, Dina   +2 more
openaire   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

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