Results 171 to 180 of about 3,940,702 (278)

The role of enterprise architecture-driven dynamic capabilities and operational digital ambidexterity in driving business value under the COVID-19 shock. [PDF]

Heliyon, 2022
van de Wetering R.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Technology change and dynamic entrepreneurial capabilities

, 2008
The paper examines how a small entrepreneurial firm can achieve successful product innovation and technology change by substituting the traditional drivers for innovation with higher order organizational capabilities.
LANZA, ANDREA, M. Passarelli
core  

A study of Chinese enterprises' business models to determine the impact of dynamic capabilities on innovation and performance. [PDF]

PLoS One
Jingwen Y, Rahman AA, Tong T, Kamarulzaman NH, Sidek SB.   +4 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Organization, Evolution, Cognition and Dynamic Capabilities [PDF]

Using insights from ‘embodied cognition’ and a resulting ‘cognitive theory of the firm’, I aim to contribute to the further development of evolutionary theory of organizations, in the specification of organizations as ‘interactors’ that carry ...
Nooteboom, B.
core  

Examining the influence of knowledge transfer and dynamic capabilities on enterprise digital transformation. [PDF]

PLoS One
Xiong X.
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Enhancing Integrated Care Through the Voluntary and Community Sector: A Lean Management and Dynamic Capabilities Perspective. [PDF]

Int J Integr Care
Tay HL.
europepmc   +1 more source

Investigating the Relationship Between the Market Orientation Approach of Pharmaceutical Companies and Their Innovative Performance: The Mediating Role of Dynamic Capabilities and Corporate Social Responsibility. [PDF]

Iran J Pharm Res, 2023
Shirmohammadi J, Azizi S, Rasekh HR, Peiravian F, Polroudi Moghaddam M.   +4 more
europepmc   +1 more source