Results 121 to 130 of about 566,262 (312)

Assessment dynamic ratio for traffic loading on highway bridges

open access: yes, 2011
The determination of characteristic bridge load effect is a complex problem. Usually, statistical extrapolation of simulated static load effects is used to derive a lifetime characteristic static load effect.
O\u27Brien, Eugene J.   +4 more
core   +1 more source

Dynamics Model and Its Verification of Aerospace Three-Ring Gear Reducer

open access: yesAerospace
This paper proposes a nonlinear dynamic modeling method based on the lumped mass approach to address the challenge of modeling the vibrations of the output external gear and internal gear plate in an aerospace three-ring gear reducer.
Jinyong Lai   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Study on the Influence of Gear Elastic Deformation on the Dynamic Characteristic of Transmission

open access: yes, 2015
Based on the theory of mechanical dynamics,the influence on dynamic characteristic of transmission is researched when the tooth generated elastic deformation under load.First,in order to build the transmission dynamic analysis model,the stiffness matrix ...
He Qu, He Jingliang, He Changran
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

On Characteristic Parameters Involved in Dynamic Fragmentation Processes

open access: yes, 2015
Dynamic loadings produce high stress waves leading to the fragmentation of brittle materials such as ceramics, concrete, glass, and rocks, or ductile ma-terials such as steels and alloys. The main mechanism used herein to explain the change of the number
Hild, François, François Hild
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Rigid-Frame Porous Material Acoustic Attenuation on Compressor Discharge

open access: yes, 2012
Standards have limited the allowable noise levels in different situations, requiring the study of solutions at the source, in the path or the receiver. Muffler is the major factor influencing the noise of rotary compressor.
Mareze, Paulo Henrique   +2 more
core  

Effect of Stiffness of Bearings and Gearbox Housing on the Dynamic characteristic of Drive System

open access: yes, 2015
The dynamic characteristic simulation analysis model of a directional drilling machine power head gearbox for different levels of complex is established based on the detailed introduction of the modeling method of main components in gearbox,the influence
Xu Liang, Shi Chunbao, Long Wei
core   +1 more source

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