Results 31 to 40 of about 3,107,467 (149)
eLife, 2014 Individuals vary in their responses to stroke and trauma, hampering predictions of outcomes. One reason might be that neural circuits contain hidden variability that becomes relevant only when those individuals are challenged by injury.
Akira Sakurai +2 more
doaj +1 more source
Frontiers in Physiology, 2023 Human-induced stem cell-derived cardiomyocytes (hiPSC-CMs) are a valuable tool for studying development, pharmacology, and (inherited) arrhythmias. Unfortunately, hiPSC-CMs are depolarized and spontaneously active, even the working cardiomyocyte subtypes
Arie O. Verkerk +2 more
doaj +1 more source
Pacemaker neuron and network oscillations depend on a neuromodulator-regulated linear current
Frontiers in Behavioral Neuroscience, 2010 Linear leak currents have been implicated in the regulation of neuronal excitability, generation of neuronal and network oscillations, and network state transitions.
Shunbing Zhao +4 more
doaj +1 more source
The Phylogenetics of Dynamics in DNA Clamp Proteins [PDF]
Structure, 2014 Using HXMS to measure protein dynamics, Fang and colleagues (in this issue of Structure) probe the dynamics of processivity clamp proteins from all kingdoms of life. The proteins have similar structures but divergent sequences. Their results show conserved dynamics correlating with primary functions and divergent dynamics for divergent functions.
Balasubramaniam, Deepa +1 more
openaire +2 more sources
Cell Reports, 2022 Summary: Protein machines undergo conformational motions to interact with and manipulate polymeric substrates. The Sec translocase promiscuously recognizes, becomes activated, and secretes >500 non-folded preprotein clients across bacterial cytoplasmic ...
Srinath Krishnamurthy +10 more
doaj +1 more source
Light-Activated Dynamic Clamp Using iPSC-Derived Cardiomyocytes [PDF]
, 2018 iPSC-derived cardiomyocytes (iPSC-CMs) are a potentially advantageous platform for drug screening because they provide a renewable source of human cardiomyocytes.
Quach, Bonnie +3 more
core +1 more source
Synchronisation through nonreciprocal connections in a hybrid hippocampus microcircuit
Frontiers in Neural Circuits, 2013 Synchronisation among neurons is thought to arise from the interplay between excitation and inhibition; however, the connectivity rules that contribute to synchronisation are still unknown.
Markus M Hilscher +2 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2020 Atrial fibrillation (AF) is the most common cardiac arrhythmia. About 5–15% of AF patients have a mutation in a cardiac gene, including mutations in KCNA5, encoding the Kv1.5 α-subunit of the ion channel carrying the atrial-specific ultrarapid delayed ...
Sarah Hilderink +5 more
doaj +1 more source
benjamin-kop/TUS-TMS-Clamp: TUS-TMS-Clamp
, 2022 Repository for 3D models of our TUS-TMS clamp ...
benjamin-kop
core +1 more source
Dynamics of a clamped–clamped microbeam resonator considering fabrication imperfections [PDF]
Microsystem Technologies, 2014 We present an investigation into the static and dynamic behavior of an electrostatically actuated clamped---clamped polysilicon microbeam resonator accounting for its fabrication imperfections, which are commonly encountered in similar microstructures.
Bataineh, Ahmad M., Younis, Mohammad I.
openaire +2 more sources