Results 91 to 100 of about 120,010 (352)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Load Parameter Identification for Parallel Robot Manipulator Based on Extended Kalman Filter

open access: yesComplexity, 2020
Load is the main external disturbance of a parallel robot manipulator. This disturbance will cause dynamic coupling among different degrees of freedom and make heaps of model-based control methods difficult to apply.
Shijie Song   +3 more
doaj   +1 more source

Man-Machine Cooperated Dynamic Schedule Orienting Disturbance in Steelmaking

open access: yes, 2011
In order to solve dynamic schedule problem brought by disturbance in steelmaking, the disturbance and corresponding method are classified. Man-machine cooperated method are brought out.
Shao Hua Dong, Ning Zhao
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Dynamic Disturbance Minimization Control for Discrete Non-Linear Stochastic Systems

open access: yes, 1993
A dynamic feedback control scheme is proposed to reduce the effect of process and measurement disturbances of known wave-form for a class of discrete non-linear stochastic systems.
Yaz, Edwin E., Azemi, Asad
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Time-Varying Characteristics of Granite Microstructures after Cyclic Dynamic Disturbance Using Nuclear Magnetic Resonance

open access: yesCrystals, 2017
To investigate the variation in the characteristics of rock microstructure after cyclic dynamic disturbances, a split Hopkinson pressure bar (SHPB) was used to carry out cyclic dynamic impact tests on granite, and the P-wave velocity was used as the ...
Chuanju Liu   +4 more
doaj   +1 more source

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