Results 91 to 100 of about 504,506 (305)
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Numerical simulation of roadway deformation and failure under different degrees of dynamic disturbance. [PDF]
Jia C +5 more
europepmc +1 more source
Adaptive Protection and Control in Power System for Wide-Area Blackout Prevention [PDF]
This paper presents a new approach in adaptive outof-step (OOS) protection settings in power system in real-time. The proposed method uses extended equal area criterion (EEAC) to determine the critical clearing time (CCT) and critical clearing angle (CCA)
Ariff, MAM, Pal, BC
core +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Dynamic Disturbance Analysis of Grasslands Using Neural Networks and Spatiotemporal Indices Fusion on the Qinghai-Tibet Plateau. [PDF]
Zou F, Hu Q, Li H, Lin J, Liu Y, Sun F.
europepmc +1 more source
Analysis of dynamic inlet distortion applied to a parallel compressor model [PDF]
An investigation of surge was conducted by using a parallel compressor model of the J85-13 compressor implement on an analog computer. Surges were initiated by various types of dynamic disturbances in inlet pressure.
Blaha, R. J., Wenzel, L. M.
core +1 more source
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source

