Results 51 to 60 of about 103,131 (263)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Advances in Civil Engineering, 2019 The mechanical characteristics of siltstone under high static load and frequent dynamic disturbance were investigated by the improved split Hopkinson pressure bar (SHPB), which is used to simulate the failure phenomenon of the extracted ore drift owing ...
Lu-ping Cheng +8 more
doaj +1 more source
Controllability measures for disturbance rejection [PDF]
Modeling, Identification and Control, 1996 Some plants have better "built-in" disturbance rejection capabilities than others, that is, their dynamic resilience (controllability) with respect to disturbance rejection is better.
Sigurd Skogestad, Erik A. Wolff
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Microgyroscopes with dynamic disturbance rejection [PDF]
SPIE Proceedings, 2001 This paper reports a novel micromachined gyroscope design with inherent disturbance-rejection capabilities. The proposed approach is based on increasing the degrees-of-freedom (DOF) of the oscillatory system by the use of two independently oscillating proof masses. Utilizing dynamical amplification in the 4-DOF system, inherent disturbance rejection is
Cenk Acar, Andrei M. Shkel
openaire +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Journal of Algorithms & Computational Technology, 2018 In order to achieve the requirements of high anti-disturbance and robustness performance for servo system, the acceleration control with disturbance observer is adopted in this paper, where the disturbance observer is used to estimate and compensate the ...
Ji Hua, Wang Shuang
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Experimental study on rock damage and failure induced by multi-source dynamic disturbances
Underground SpaceResearch into the mechanical behaviour of rock surrounding the deep-buried tunnel under multi-source dynamic disturbance is key to the safety of underground engineering operations.
Han-Yi Liu +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source