Results 61 to 70 of about 504,506 (305)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Voltage Multistability and Pulse Emergency Control for Distribution System with Power Flow Reversal [PDF]

, 2015
High levels of penetration of distributed generation and aggressive reactive power compensation may result in the reversal of power flows in future distribution grids.
Nguyen, Hung D., Turitsyn, Konstantin
core   +2 more sources

Dynamic Stall Control by Passive Disturbance Generators [PDF]

AIAA Journal, 2011
Passive cylindrical disturbance generators mounted near the leading edge of an airfoil significantly improved its performance under dynamic stall conditions. Time-resolved particle image velocimetry and simultaneous pressure measurements were conducted at the midchord of a pitching airfoil equipped with passive disturbance generators.
Heine, Benjamin, Mulleners, Karen, Joubert, Gilles, Raffel, Markus   +3 more
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Study on Dynamic Characteristics of Deep Siltstone under High Static Stress and Frequent Dynamic Disturbance

Advances in Civil Engineering, 2019
The mechanical characteristics of siltstone under high static load and frequent dynamic disturbance were investigated by the improved split Hopkinson pressure bar (SHPB), which is used to simulate the failure phenomenon of the extracted ore drift owing ...
Lu-ping Cheng, Chun Wang, Li-zhong Tang, Cheng Wang, Zhu-qiang Xiong, Shi-ming Wei, Yuan Chen, Tao Liu, Yong-heng Wei   +8 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Research on anti-disturbance performance for servo system with a high dynamic performance velocity acquisition method

Journal of Algorithms & Computational Technology, 2018
In order to achieve the requirements of high anti-disturbance and robustness performance for servo system, the acceleration control with disturbance observer is adopted in this paper, where the disturbance observer is used to estimate and compensate the ...
Ji Hua, Wang Shuang
doaj   +1 more source

Controllability measures for disturbance rejection [PDF]

Modeling, Identification and Control, 1996
Some plants have better "built-in" disturbance rejection capabilities than others, that is, their dynamic resilience (controllability) with respect to disturbance rejection is better.
Sigurd Skogestad, Erik A. Wolff
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source