Results 61 to 70 of about 111,217 (264)

Experimental study on rock damage and failure induced by multi-source dynamic disturbances

Underground Space
Research into the mechanical behaviour of rock surrounding the deep-buried tunnel under multi-source dynamic disturbance is key to the safety of underground engineering operations.
Han-Yi Liu, Ben-Guo He, Jia-Hua Guan, Hong-Yuan Fu   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

AERODYNAMIC DISTURBANCE ON VEHICLE’S DYNAMIC PARAMETERS [PDF]

Journal of Engineering Science and Technology, 2018
This research paper analysed the influence of aerodynamic disturbance on vehicle’s dynamic parameters. The vehicle dynamics were formulated from the Newton’s Second Law for modelling the vehicle.
MU’AZU J. MUSA, SHAHDAN SUDIN, ZAHARUDDIN MOHAMED   +2 more
doaj  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Dynamic Shear Strength of Rock Joints and Its Influence on Key Blocks

Geofluids, 2019
Shear strength deterioration of rock joints and its induced instability of key blocks subjected to dynamic disturbance constitute the mechanism of many geological disasters such as rockburst, landslide, and rockfall.
Shuhong Wang, Feili Wang, Zhanguo Xiu
doaj   +1 more source

Indirect Measurement of Rotor Dynamic Imbalance for Control Moment Gyroscopes via Gimbal Disturbance Observer

Sensors, 2018
The high-precision speed control of gimbal servo systems is the key to generating high-precision torque for control moment gyroscopes (CMGs) in spacecrafts.
Liya Huang, Zhong Wu, Kan Wang
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

The influence of disturbance location and intensity on the deformation and failure of deep roadway surrounding rocks

Frontiers in Materials
The surrounding rocks in deep roadways frequently undergo dynamic disturbances caused by adjacent blasting or mining activities. These dynamic disturbances lead to the propagation and coalescence of cracks in the surrounding rock, inducing dynamic ...
Tao Zhang, Yunyun Xu, Chao Wei, Haijian Su, Yujie Feng, Liyuan Yu   +5 more
doaj   +1 more source