Results 61 to 70 of about 5,754,265 (320)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Study on Dynamic Characteristics of Deep Siltstone under High Static Stress and Frequent Dynamic Disturbance

open access: yesAdvances in Civil Engineering, 2019
The mechanical characteristics of siltstone under high static load and frequent dynamic disturbance were investigated by the improved split Hopkinson pressure bar (SHPB), which is used to simulate the failure phenomenon of the extracted ore drift owing ...
Lu-ping Cheng   +8 more
doaj   +1 more source

Controllability measures for disturbance rejection [PDF]

open access: yesModeling, Identification and Control, 1996
Some plants have better "built-in" disturbance rejection capabilities than others, that is, their dynamic resilience (controllability) with respect to disturbance rejection is better.
Sigurd Skogestad, Erik A. Wolff
doaj   +1 more source

Human Like Adaptation of Force and Impedance in Stable and Unstable Tasks [PDF]

open access: yes, 2011
—This paper presents a novel human-like learning con-troller to interact with unknown environments. Strictly derived from the minimization of instability, motion error, and effort, the controller compensates for the disturbance in the environment in ...
Albu-Schaeffer, A   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Research on anti-disturbance performance for servo system with a high dynamic performance velocity acquisition method

open access: yesJournal of Algorithms & Computational Technology, 2018
In order to achieve the requirements of high anti-disturbance and robustness performance for servo system, the acceleration control with disturbance observer is adopted in this paper, where the disturbance observer is used to estimate and compensate the ...
Ji Hua, Wang Shuang
doaj   +1 more source

Dynamic Stall Control by Passive Disturbance Generators [PDF]

open access: yesAIAA Journal, 2011
Passive cylindrical disturbance generators mounted near the leading edge of an airfoil significantly improved its performance under dynamic stall conditions. Time-resolved particle image velocimetry and simultaneous pressure measurements were conducted at the midchord of a pitching airfoil equipped with passive disturbance generators.
Heine, Benjamin   +3 more
openaire   +3 more sources

Voltage Multistability and Pulse Emergency Control for Distribution System with Power Flow Reversal [PDF]

open access: yes, 2015
High levels of penetration of distributed generation and aggressive reactive power compensation may result in the reversal of power flows in future distribution grids.
Nguyen, Hung D., Turitsyn, Konstantin
core   +2 more sources

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