Results 101 to 110 of about 3,584,282 (275)

Tourist Circuits Map Mechanism for Developing Mountain Tourism: An Applied Study of the Sefrou Province [PDF]

E3S Web of Conferences
The geological and geomorphological sites in the Sefrou region of Morocco represent key assets for sustainable mountain tourism, given their diversity and richness in landscape natural phenomena.
Chami Jaouad, Elbachiri Zouhir, En-Nejymy Mohamed, Achkir Hadou, El Khalki Yahya, El Azzioui Said   +5 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

PSD-based intersection method for photoelectric detection of explosion position in field environments

AIP Advances
Accurate explosion localization is critical in defense research and civil blasting engineering, serving as a core technology in weapon development and controlled demolition.
Wenbo Chu, Pengfei Wang, Bin Zhang, Yuan Li, Donge Zhao   +4 more
doaj   +1 more source

Research on Road Surface Recognition Algorithm Based on Vehicle Vibration Data

Sensors
Road surface conditions significantly impact driving safety and maintenance costs. Especially in connected and automated vehicles (CAVs), the road surface type recognition is critical for environmental perception.
Jianfeng Cui, Hengxu Zhang, Xiao Wang, Yu Jing, Xiujian Chou   +4 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

An Adaptive Unscented Kalman Ilter Integrated Navigation Method Based on the Maximum Versoria Criterion for INS/GNSS Systems

Sensors
Aimed at the problem of navigation performance degradation in inertial navigation system/global navigation satellite system (INS/GNSS)-integrated navigation systems due to measurement anomalies and non-Gaussian measurement noise in complex navigation ...
Jiahao Zhang, Kaiqiang Feng, Jie Li, Chunxing Zhang, Xiaokai Wei   +4 more
doaj   +1 more source

Flow dynamic environment data base development for the SSME [PDF]

The fluid flow-induced vibration of the Space Shuttle main engine (SSME) components are being studied with a view to correlating the frequency characteristics of the pressure fluctuations in a rocket engine to its operating conditions and geometry.
Sundaram, C. V.
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Simultaneous localization and mapping in a multi-robot system in a dynamic environment with unknown initial correspondence. [PDF]

Front Robot AI, 2023
Malakouti-Khah H, Sadeghzadeh-Nokhodberiz N, Montazeri A.   +2 more
europepmc   +1 more source