Results 131 to 140 of about 3,597,207 (294)

Editorial: The embodied brain: computational mechanisms of integrated sensorimotor interactions with a dynamic environment, volume II. [PDF]

Front Comput Neurosci, 2023
Röhrbein F, Senden M.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

SLP-Improved DDPG Path-Planning Algorithm for Mobile Robot in Large-Scale Dynamic Environment. [PDF]

Sensors (Basel), 2023
Chen Y, Liang L.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

From waste to strength: The role of FGD gypsum in loess stabilization and its environmental benefits

iScience
Summary: Loess exhibits high porosity and structural vulnerability, presenting serious geotechnical challenges in arid and semi-arid regions. In this study, the use of flue gas desulfurization (FGD) gypsum, a coal combustion by-product, as a sustainable ...
Yuan Kangze, Xie Wanli, Gao Xuanyu, Li Xinyu, Liu Qiqi   +4 more
doaj   +1 more source

Atypical action updating in a dynamic environment associated with adolescent obsessive-compulsive disorder. [PDF]

J Child Psychol Psychiatry, 2022
Marzuki AA, Vaghi MM, Conway-Morris A, Kaser M, Sule A, Apergis-Schoute A, Sahakian BJ, Robbins TW.   +7 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Challenges of Periodontal Tissue Engineering: Increasing Biomimicry through 3D Printing and Controlled Dynamic Environment. [PDF]

Nanomaterials (Basel), 2022
Roato I, Masante B, Putame G, Massai D, Mussano F.   +4 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

RGB-D Visual SLAM Based on Yolov4-Tiny in Indoor Dynamic Environment. [PDF]

Micromachines (Basel), 2022
Chang Z, Wu H, Sun Y, Li C.
europepmc   +1 more source