Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
SIMULATION OF CONTROL PROCESSES OF PROJECTS’ RESOURCE FLOWS
Вісник Національного технічного університету «ХПÌ». Серія: Стратегічне управління, управління портфелями, програмами та проектами, 2015 The features of the control resource flows projects and programs are considered. The agent-based simulation model of dynamic analysis of resource management processes in implementation of the enterprise project portfolio, which considers a number of ...
Сергей Геннадиевич КИЙКО
doaj +1 more source
Dynamic Coupling of Convective Flows and Magnetic Field during Flux Emergence [PDF]
, 2011 We simulate the buoyant rise of a magnetic flux rope from the solar convection zone into the corona to better understand the energetic coupling of the solar interior to the corona. The magnetohydrodynamic model addresses the physics of radiative cooling,
Abbett +35 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Dynamic flow and shear stress as key parameters for intestinal cells morphology and polarization in an organ-on-a-chip model [PDF]
, 2021 Chiara Fois +3 more
openalex +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
A Machine-Learning-Assisted Simulation Approach for Incorporating Predictive Maintenance in Dynamic Flow-Shop Scheduling [PDF]
, 2021 Eman Azab +3 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
ACCOUNTING INFLUENCE OF CENTRIFUGAL FORCE IN THE NUMERICAL MODELING OF RISING SWIRLED GAS FLOW
Известия высших учебных заведений: Нефть и газ, 2015 In work the consistent inclusion of centrifugal force in the numerical calculations of three-dimensional gas-dynamic characteristics of the unsteady flow of compressible viscous heat-conducting gas in an upward swirling flow caused by the vertical cold ...
S. P. Bautin, A. G. Obukhov
doaj +1 more source
Dynamic Modeling for Metro Passenger Flows on Congested Transfer Routes
Mathematics, 2023 With the rapid development of urbanization, the metro becomes more and more important for people’s travel in big cities. To quantitatively describe metro passenger flows on congested transfer routes, this paper introduces a dynamic model based on ...
Weiyan Mu +3 more
doaj +1 more source