Results 51 to 60 of about 72,806 (265)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Vortex Dynamics of Oscillating Flows [PDF]
Arnold Mathematical Journal, 2015 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Vladimirov, V. A. +2 more
openaire +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Time Can Flow in the Opposite Direction of What We Think It Does
ProblemosAttitudes towards the future and the past differ. This difference seems easy to explain if time actually flows, and thus, has an intrinsic direction. At first, this appears to be an advantage of the dynamic view of time, according to which time really ...
Kunihisa Morita
doaj +1 more source
Flow dynamics and haemostasis.
Annali dell'Istituto superiore di sanita, 2007 Fluid-dynamic conditions that are compatible with tensile stress on the bonds between platelet glycoprotein Ibalpha and immobilized Von Willebrand factor A1 domain (VWF-A1) led to Ca++ release from intracellular stores (type alpha/beta peaks), which preceded stationary platelet adhesion. Raised levels of cyclic adenosine monophosphate (cAMP) and cyclic
M. MAZZUCATO +4 more
openaire +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Detailed Wake Structure behind an Elastic Airfoil
Journal of Fluid Science and Technology, 2009 An unsteady flow in a low Reynolds number region attracts attention in recent years. The authors measured vortex flow in the wake of the rigid flat plate, rigid NACA0010, elastic flat plate and elastic NACA0010 with heaving motions and evaluated ...
Masaki FUCHIWAKI +2 more
doaj +1 more source
Scheduling Enhancements and Performance Evaluation of Downlink 5G Time-Sensitive Communications
IEEE Access, 2020 Time-sensitive communications (TSC) in wireless networks is an emerging paradigm that gains research momentum as an enabler of the industrial Internet of Things.
Renato B. Abreu +5 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source