Results 61 to 70 of about 909,603 (328)
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
Detailed Wake Structure behind an Elastic Airfoil
An unsteady flow in a low Reynolds number region attracts attention in recent years. The authors measured vortex flow in the wake of the rigid flat plate, rigid NACA0010, elastic flat plate and elastic NACA0010 with heaving motions and evaluated ...
Masaki FUCHIWAKI+2 more
doaj +1 more source
Continuity of the Effective Path Delay Operator for Networks Based on the Link Delay Model [PDF]
This paper is concerned with a dynamic traffic network performance model, known as dynamic network loading (DNL), that is frequently employed in the modeling and computation of analytical dynamic user equilibrium (DUE).
Friesz, Terry L., Han, Ke
core
MELODIE: A whole-farm model to study the dynamics of nutrients in dairy and pig farms with crops [PDF]
In regions of intensive pig and dairy farming, nutrient losses to the environment at farm level are a source of concern for water and air quality. Dynamic models are useful tools to evaluate the effects of production strategies on nutrient flows and ...
Baratte, C.+17 more
core +3 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Scheduling Enhancements and Performance Evaluation of Downlink 5G Time-Sensitive Communications
Time-sensitive communications (TSC) in wireless networks is an emerging paradigm that gains research momentum as an enabler of the industrial Internet of Things.
Renato B. Abreu+5 more
doaj +1 more source
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa+8 more
wiley +1 more source
Dynamic Electroosmotic Flows of Power-Law Fluids in Rectangular Microchannels
Dynamic characteristics of electroosmosis of a typical non-Newtonian liquid in a rectangular microchannel are investigated by using numerical simulations.
Cunlu Zhao, Wenyao Zhang, Chun Yang
doaj +1 more source