Results 71 to 80 of about 1,355,767 (260)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Initial dynamic load estimates during configuration design [PDF]
This analysis includes the structural response to shock and vibration and evaluates the maximum deflections and material stresses and the potential for the occurrence of elastic instability, fatigue and fracture.
Schiff, Daniel
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Simplified Algorithm for Dynamic Demand Response in Smart Homes Under Smart Grid Environment
, 2019 Under Smart Grid environment, the consumers may respond to incentive--based smart energy tariffs for a particular consumption pattern. Demand Response (DR) is a portfolio of signaling schemes from the utility to the consumers for load shifting/shedding ...
Namboodiri, Aryesh +2 more
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Dynamic Loadings Of Precastretaining Walls
Kirkuk University Journal-Scientific Studies, 2007 The research aims for the selection of a suitable retaining wall amongst two types of precast concrete walls under dynamic loads (wave pressure). The first wall is of a triangular cross section and has the dimensions (3)m (in height) by (2.2) m (in width) by (0.25-0.3) m (in thickness) and the width of piece (1.44) m. The second wall has dimensions of (
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Cluster-Based Load Balancing Algorithms for Grids
, 2011 E-science applications may require huge amounts of data and high processing power where grid infrastructures are very suitable for meeting these requirements. The load distribution in a grid may vary leading to the bottlenecks and overloaded sites.
Dagdeviren, Orhan +2 more
core
Influence of dynamic load and water on energy accumulation and dissipation in sandstone. [PDF]
Sci Rep, 2023 Yang Y +7 more
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Loading device for oncoming dynamic loading
Traktory i sel hozmashiny, 2014 Methods of running and testing of parts, units and aggregates under load in case of transferring required drive torques through them are considered. The method of loading by oncoming drive torques using inertial loaders is theoretically substantiated.
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