Results 111 to 120 of about 610,012 (310)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Application of numerical simulation studies to determine dynamic loads acting on the human masticatory system during unilateral chewing of selected foods. [PDF]
Front Bioeng Biotechnol, 2023 Stróżyk P, Bałchanowski J.
europepmc +1 more source
Dynamic tooth loads and stressing for high contact ratio spur gears [PDF]
, 1983 An analysis and computer program were developed for calculating the dynamic gear tooth loading and root stressing for high contact ratio gearing (HCRG) as well as LCRG.
Cornell, R. W., Westervelt, W. W.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Dynamic Performance of a Decoupled Dual Wound Synchronous Generator for Electric Propulsion of Ships
IEEE AccessThe dual wound generator brings significant advantages to integrated electric propulsion systems in ships, particularly in terms of footprint reduction and space saving.
Han Wang +4 more
doaj +1 more source
Experimental Study on Mechanical Properties and Failure Laws of Granite with Artificial Flaws under Coupled Static and Dynamic Loads. [PDF]
Materials (Basel), 2022 Li G, Liu S, Lu R, Ma F, Guo J.
europepmc +1 more source
Theoretical dynamic analysis of the landing loads on a vehicle with a tricycle landing gear [PDF]
Theoretical dynamic analysis of landing loads on vehicle with tricycle landing gear compared with X-15 aircraft ...
Mc Kay, J. M., Noll, R. B.
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source