Results 91 to 100 of about 137,150 (318)
The development of a dynamic amplification estimator for bridges with good road profiles
, 2006 The paper considers the influence of the surface profile on the dynamic amplification of a simply supported bridge when subject to a quarter car vehicle model.
O'Brien, Eugene J. +2 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Development of Aircraft Flight Loads Analysis Models with Uncertainties for Pre-Design Studies
, 2005 This paper addresses the development of analysis tools for flight loads prediction in the pre-design stage. The analysis tools are embedded in a parametric modelling environment.
Looye, Gertjan +2 more
core
Assessment of the Dynamic Loads Effect on Underground Mines Supports [PDF]
, 2011 Blasting operations generate seismic effects in underground mines. These effects apply additional dynamic loads on the support system, which should bear both static and dynamic loads.
Goodarzi, Arash +2 more
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Safe dynamic design of structures. [PDF]
, 2000 The Design of structures under dynamic loading is a demanding subject in safety of engineering design since conventional static failure criteria are unable to deal with structures under transient loading.
Moatamedi, Mojtaba, Moatamedi, M.
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Dynamic characteristics of steel-deck composite floors under human induced loads
, 2009 Steel-deck composite floor systems are a popular choice in high-rise buildings as they are economical and easy to construct. These composite floor systems use high strength materials to achieve longer spans, but are slender and vulnerable to vibration ...
De Silva, Sandun S. +1 more
core +1 more source
Dynamic mechanical loads on PV-modules
, 2022 S.3395 - 3397Photovoltaic (PV)-modules are not only exposed to static mechanical loads, such as snow and wind loads (for building integrated modules), as tested in the current standard IEC 61215.
Köhl, Michael +3 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source