Results 101 to 110 of about 395,732 (262)

U.S. and Whom? Structures and Communities of International Economic Research [PDF]

Journal of Social Structure, 2015
Raphael H. Heiberger, Jan R. Riebling
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Energy and Spectral Efficiency Analysis for UAV-to-UAV Communication in Dynamic Networks for Smart Cities

Smart Cities
Unmanned Aerial Vehicles (UAVs) are integral to the development of smart city infrastructures, enabling essential services such as real-time surveillance, urban traffic regulation, and cooperative environmental monitoring.
Mfonobong Uko, Sunday Ekpo, Ubong Ukommi, Unwana Iwok, Stephen Alabi   +4 more
doaj   +1 more source

Modeling homophily in dynamic networks with application to HIV molecular surveillance. [PDF]

BMC Infect Dis, 2023
DeGruttola V, Nakazawa M, Lin T, Liu J, Goyal R, Little S, Tu X, Mehta S.   +7 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Attention-Based Anomaly Detection in Dynamic Network

Big Data Mining and Analytics
Detecting anomalies in dynamic networks is essential for a range of real-world applications, such as social networks and cybersecurity. However, it encounters substantial challenges due to the diverse and ever-evolving nature of these anomalies.
Yiming Zhao, Wenjun Wang, Nannan Wu, Jilei Liu, Ying Sun, Wei Yu, Quannan Zu   +6 more
doaj   +1 more source

Thermally Reversible Organocatalyst for the Accelerated Reprocessing of Dynamic Networks with Creep Resistance. [PDF]

ACS Macro Lett, 2023
Vozzolo G, Ximenis M, Mantione D, Fernández M, Sardon H.   +4 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source