Results 161 to 170 of about 395,732 (262)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Dynamic networks of fluorine-rich acrylates enable highly conductive and flame-retardant electrolytes for lithium metal batteries. [PDF]

Chem Sci
Gan J, Zhao Y, Jiang Z, Yang C, Ke D, Wang Q, Liu Y, Zeng X, Zhou T.   +8 more
europepmc   +1 more source

The role of lateral erosion in the evolution of nondendritic drainage networks to dendricity and the persistence of dynamic networks. [PDF]

Proc Natl Acad Sci U S A, 2021
Kwang JS, Langston AL, Parker G.
europepmc   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Dynamic Networks of Methicillin-Resistant <i>Staphylococcus aureus</i> in Communities Drive Hospital Transmission. [PDF]

Open Forum Infect Dis
Cohen SA, Tagliamonte MS, Mavian C, Iovine NM, Zhai Y, Jeong KC, Prosperi M, Tyndall JA, Salemi M, Morris JG.   +9 more
europepmc   +1 more source

Integration of photocatalytic and dark-operating catalytic biomimetic transformations through DNA-based constitutional dynamic networks. [PDF]

Nat Commun, 2021
Wang C, O'Hagan MP, Neumann E, Nechushtai R, Willner I.   +4 more
europepmc   +1 more source

Temporal Trends in and Associations With Nonsteroidal Anti‐inflammatory Drug Prescription in Adult and Pediatric Patients With Inflammatory Bowel Disease

Arthritis Care &Research, EarlyView.
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer, Rui Xiao, Andrew Grossman, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +5 more
wiley   +1 more source

The future of dynamic networks in research and clinical practice. [PDF]

World Psychiatry
Bringmann LF.
europepmc   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Identification of dynamic networks community by fusing deep learning and evolutionary clustering. [PDF]

Sci Rep
Pan Y, Liu X, Yao F, Zhang L, Li W, Wang P.   +5 more
europepmc   +1 more source